3-Hydroxy-2-methylpropanenitrile

Base Information

Chemical Name:3-Hydroxy-2-methylpropanenitrile
CAS No.:2567-01-3
Molecular Formula:C4H7 N O
Molecular Weight:85.1057
Hs Code.:
European Community (EC) Number:219-902-2
DSSTox Substance ID:DTXSID50948549
Nikkaji Number:J192.073A
Mol file:2567-01-3.mol

Synonyms:3-hydroxy-2-methylpropanenitrile;2567-01-3;PROPYLENE CYANOHYDRIN;3-Hydroxy-2-methylpropiononitrile;Propanenitrile, 3-hydroxy-2-methyl-;beta-hydroxyisobutyronitrile;2-(Hydroxymethyl)propanenitrile;DTXSID50948549;EINECS 219-902-2;MFCD11653306;AKOS009387606;CS-0222830;EN300-112802;Z406338220

Suppliers and Price of 3-Hydroxy-2-methylpropanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
3-hydroxy-2-methylpropanenitrile
100mg
$ 280.00

AK Scientific
3-hydroxy-2-methylpropanenitrile
20mg
$ 180.00

Total 6 raw suppliers

Chemical Property of 3-Hydroxy-2-methylpropanenitrile

Chemical Property:

Vapor Pressure:0.0286mmHg at 25°C
Boiling Point:
Vapour density:
Flash Point:85.2°C
PSA：44.02000
Density:0.991g/cm³
LogP:0.13838
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:85.052763847
Heavy Atom Count:6
Complexity:70.9

Purity/Quality:

99% ^*data from raw suppliers

3-hydroxy-2-methylpropanenitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CO)C#N

Technology Process of 3-Hydroxy-2-methylpropanenitrile

There total 6 articles about 3-Hydroxy-2-methylpropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 28539-02-8
1-Hydroxymethyl-1H-benzotriazole

: 107-12-0
propiononitrile

: 2567-01-3
3-hydroxy-2-methylpropanonitrile

Guidance literature:: propiononitrile; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

1-Hydroxymethyl-1H-benzotriazole; In tetrahydrofuran; at -78 ℃; for 2h;
DOI:10.1021/ol070145b

Reference yield:

: 151-50-8
potassium cyanide

: 75-56-9,16033-71-9
methyloxirane

3-hydroxybutanenitrile: 4368-06-3
3-hydroxybutanenitrile

: 623-35-8
1,2-dicyanopropane

: 2567-01-3
3-hydroxy-2-methylpropanonitrile

Guidance literature:: ammonium chloride; In methanol; water; for 24h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;
DOI:10.1016/S0040-4039(00)92305-0

Reference yield:

: 7677-24-9
trimethylsilyl cyanide

: 75-56-9,16033-71-9
methyloxirane

3-hydroxybutanenitrile: 4368-06-3
3-hydroxybutanenitrile

: 2567-01-3
3-hydroxy-2-methylpropanonitrile

Guidance literature:: With trimethylaluminum; cesium fluoride; Multistep reaction. Title compound not separated from byproducts; 1) CH₂Cl₂, r.t., 2) MeOH, r.t., 1 h;
DOI:10.1021/jo00038a032