623-35-8Relevant academic research and scientific papers
METHOD FOR PRODUCING METHYLSUCCINONITRILE OR SUCCINONITRILE
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Paragraph 0043-0114, (2020/02/04)
PROBLEM TO BE SOLVED: To produce methylsuccinonitrile or succinonitrile with high purity. SOLUTION: In the presence of organic solvent, a reaction is caused to occur among methacrylonitrile or acrylonitrile, a cyan compound, a basic catalyst, and a chain polyether compound, to obtain methylsuccinonitrile or succinonitrile by fractionation. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT
Easy Direct Stereo- and Regioselective Formation of β-Hydroxy Nitriles by Reaction of 1,2-Epoxides with Potassium Cyanide in the Presence of Metal Salts
Chini, Marco,Crotti, Paolo,Favero, Lucilla,Macchia, Franco
, p. 4775 - 4778 (2007/10/02)
A simple efficient, anti stereoselective, and highly regioselective method for the synthesis of β-hydroxy nitriles by the direct opening of 1,2-epoxides with KCN in acetonitrile, in the presence of metal salts, is described.This new method appears to be competitive with the other methods previously reported. Key words: β-hydroxy nitriles; epoxide opening reactions; regioselectivity; catalysts.
