(E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea

Base Information

• Chemical Name: (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea
• CAS No.: 1607822-68-3
• Molecular Formula: C₂₀H₂₁N₃O₃S
• Molecular Weight: 383.471

Synonyms:(E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea

Chemical Property of (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea

There total 5 articles about (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.2%

(E)-N-methoxy-N-(2-((1-(1H-benzo[b]thien-2-yl)ethylidene)aminooxy-methyl)phenyl)carbamic acid methyl ester (1607822-60-5) + methylamine (74-89-5) → (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea (1607822-68-3)

Guidance literature:

In methanol; Reflux;

DOI:10.1016/j.bmcl.2014.03.024

Reference yield:

2-chloro-benzaldehyde (89-98-5) → (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea (1607822-68-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydroxide / water / 0.5 h / 20 °C

1.2: 82 °C

2.1: calcium oxide / acetone / 59 °C

3.1: hydroxylamine hydrochloride; sodium acetate / water; ethanol / Reflux

4.1: potassium carbonate / acetonitrile / Reflux

5.1: methanol / Reflux

With hydroxylamine hydrochloride; sodium acetate; potassium carbonate; sodium hydroxide; calcium oxide; In methanol; ethanol; water; acetone; acetonitrile;

DOI:10.1016/j.bmcl.2014.03.024

Reference yield:

2-acetylbenzothiophene oxime (147396-07-4) → (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea (1607822-68-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / Reflux

2: methanol / Reflux

With potassium carbonate; In methanol; acetonitrile;

DOI:10.1016/j.bmcl.2014.03.024

upstream raw materials:

2-acetylbenzothiophene oxime

2-(ethylsulfanyl)benzenecarbaldehyde

(E)-N-methoxy-N-(2-((1-(1H-benzo[b]thien-2-yl)ethylidene)aminooxy-methyl)phenyl)carbamic acid methyl ester

methylamine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1607822-68-3 (E)-1-methoxy-3-methyl-1-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)urea

Send

Send

Metric Ton KG G Pound L ML

Send

Send