10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine

Base Information

Chemical Name:10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine
CAS No.:1207516-29-7
Molecular Formula:C₂₂H₁₉F₂N₃O
Molecular Weight:379.409
Hs Code.:

Synonyms:10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine

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Chemical Property of 10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine

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Technology Process of 10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine

There total 1 articles about 10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1207516-28-6
ethyl 10-fluoro-6-(3-fluoro-4-methoxybenzyl)-1,2,4,7-tetrahydro-3H-indolo[2,3-c][1,7]naphthyridine-3-carboxylate

: 1207516-29-7
10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine

Guidance literature:: With hydrazine hydrate; potassium hydroxide; In ethylene glycol; at 140 ℃; for 2h;

Reference yield: 72.0%

: 683-57-8
bromo-acetic acid amide

: 1207516-29-7
10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine

: 1207516-37-7
2-[10-fluoro-6-(3-fluoro-4-methoxybenzyl)-1,2,4,7-tetrahydro-3H-indolo[2,3-c][1,7]naphthyridin-3-yl]acetamide

Guidance literature:: With potassium carbonate; In acetone; at 20 - 25 ℃; for 18h;

Reference yield: 64.0%

: 1207516-29-7
10-fluoro-6-(3-fluoro-4-methoxybenzyl)-2,3,4,7-tetrahydro-1H-indolo[2,3-c][1,7]naphthyridine

: 64-19-7,77671-22-8
acetic acid

: 1207516-30-0
1-[10-fluoro-6-(3-fluoro-4-methoxybenzyl)-1,2,4,7-tetrahydro-3H-indolo[2,3-c][1,7]naphthyridin-3-yl]ethanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 - 25 ℃; for 18h;