DANSYL ETHYLENEDIAMINE

Base Information

• Chemical Name: DANSYL ETHYLENEDIAMINE
• CAS No.: 35060-08-3
• Molecular Formula: C14H19 N3 O2 S
• Molecular Weight: 293.38
• Hs Code.: 2935009090
• Mol file: 35060-08-3.mol

Synonyms:2-(5-Dimethylamino-1-naphthalenesulfonamido)ethylamine;Dansylethylenediamine; N-(2-Aminoethyl)-5-(N,N-dimethylamino)naphthalene-1-sulfonamide;N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide;N-(Dansyl)ethylenediamine; NSC 666752

Chemical Property of DANSYL ETHYLENEDIAMINE

Chemical Property:

• Vapor Pressure: 5.19E-09mmHg at 25°C
• Melting Point: 145-146°C
• Boiling Point: 470.2°Cat760mmHg
• Flash Point: 238.1°C
• PSA: 83.81000
• Density: 1.262g/cm³
• LogP: 3.31480
• Storage Temp.: -20?C Freezer
• Solubility.: methanol: soluble1mg/mL, clear, slightly yellow to deep yellow

Purity/Quality:

97% ^*data from raw suppliers

Dansyl Ethylenediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A fluorescent reagent.

Technology Process of DANSYL ETHYLENEDIAMINE

There total 19 articles about DANSYL ETHYLENEDIAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-(dimethylamino)naphth-1-ylsulfonyl chloride (605-65-2) + ethylenediamine (107-15-3,85404-18-8) → dansylethylenediamine (35060-08-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1246/cl.2004.452

Reference yield: 87.0%

9-fluorenylmethyl N-(N-(2-dansyl)-2-aminoethyl)-carbamate (1207722-28-8) → dansylethylenediamine (35060-08-3)

Guidance literature:

With morpholine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

DOI:10.1021/jm9016043

Reference yield: 81.0%

tert-butyl 2-(5-(dimethylamino)naphthalene-1-sulfonamido)ethylcarbamate (160291-44-1) → dansylethylenediamine (35060-08-3)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1039/c3cc39105a

upstream raw materials:

5-(dimethylamino)naphth-1-ylsulfonyl chloride

ethylenediamine

N-<(5-dimethylamino-1-naphthalenesulfonamido)ethyl>phthalimide

tert-butyl 2-(5-(dimethylamino)naphthalene-1-sulfonamido)ethylcarbamate

Downstream raw materials:

2-amino-N-{1-[1-(1-{1-[2-(5-dimethylamino-naphthalene-1-sulfonylamino)-ethylcarbamoyl]-2-phenyl-ethylcarbamoyl}-2-hydroxy-ethylcarbamoyl)-2-hydroxy-ethylcarbamoyl]-2-hydroxy-ethyl}-3-hydroxy-propionamide

C₁₄H₁₉N₃O₂S*ClH

C₃₀H₃₅N₃O₃S

AL₁₉₄