4-(5-Chloro-2-methoxyphenyl)butanoic acid

Base Information

Chemical Name:4-(5-Chloro-2-methoxyphenyl)butanoic acid
CAS No.:63213-95-6
Molecular Formula:C₁₁H₁₃ClO₃
Molecular Weight:228.675
Hs Code.:
DSSTox Substance ID:DTXSID601282740
Wikidata:Q107856338

Synonyms:63213-95-6;4-(5-chloro-2-methoxyphenyl)butanoic acid;SCHEMBL7412627;MSOJPOUMDCUNHP-UHFFFAOYSA-N;DTXSID601282740;2-(3-Carboxypropyl)-4-chloroanisole;AKOS017559839;5-Chloro-2-methoxybenzenebutanoic acid;4-(5-chloro-2-methoxyphenyl)butyric acid

Suppliers and Price of 4-(5-Chloro-2-methoxyphenyl)butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(5-Chloro-2-methoxyphenyl)butanoic acid

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:228.0553220
Heavy Atom Count:15
Complexity:208

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Cl)CCCC(=O)O

Technology Process of 4-(5-Chloro-2-methoxyphenyl)butanoic acid

There total 3 articles about 4-(5-Chloro-2-methoxyphenyl)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 63213-94-5
5-chloro-2-methoxy-γ-oxobenzenebutanoic acid

: 63213-95-6
4-(5-chloro-2-methoxyphenyl)butanoic acid

Guidance literature:: With triethylsilane; trifluoroacetic acid; at 20 ℃; for 6h; Inert atmosphere;
DOI:10.1021/acs.jnatprod.8b00258

Reference yield:

: 623-12-1
4-chloromethoxybenzene

: 63213-95-6
4-(5-chloro-2-methoxyphenyl)butanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: AlCl₃

2: amalgamated zinc; aqueous HCl

With hydrogenchloride; aluminium trichloride; amalgamated zinc;
DOI:10.1021/jo01093a037