63213-94-5Relevant academic research and scientific papers
Total Synthesis and Structure Revision of Palmarumycin B6
Liu, Xinlei,Wang, Weiwei,Zhao, Yu,Lai, Daowan,Zhou, Ligang,Liu, Zhilong,Wang, Mingan
, p. 1803 - 1809 (2018/09/10)
Palmarumycin B6 and its regioisomer were synthesized via 7- and 13-step routes using 2-chlorophenol and 4-chlorophenyl methyl ether as the starting materials in overall yields of 2.7% and 12%, respectively. Their structures were characterized b
Piperazinyl CCR1 antagonists-optimization of human liver microsome stability
Brown, Matthew F.,Bahnck, Kevin B.,Blumberg, Laura C.,Brissette, William H.,Burrell, Sara A.,Driscoll, James P.,Fedeles, Flavia,Fisher, Michael B.,Foti, Robert S.,Gladue, Ronald P.,Guzman-Martinez, Aikomari,Hayward, Matthew M.,Lira, Paul D.,Lillie, Brett M.,Lu, Yi,Lundquist, Greg D.,McElroy, Eric B.,McGlynn, Molly A.,Paradis, Timothy J.,Poss, Christopher S.,Roache, James H.,Shavnya, Andrei,Shepard, Richard M.,Trevena, Kristen A.,Tylaska, Laurie A.
, p. 3109 - 3112 (2008/03/13)
The synthesis, biological activity, and pharmacokinetic profile of CCR1 antagonists are described.
2-Aminomethyl-3,4-dihydronaphthalenes
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, (2008/06/13)
Compounds of the formula STR1 and pharmaceutically acceptable salts thereof, wherein X and Y are independently H, F, Cl, Br, alkyl having up to four carbons, or alkoxy having up to four carbons, but X and Y are not both H, and Z is a secondary or tertiary amino group, are useful as analgesics and tranquillizing agents for mammals.
