cholest-5-en-3β-yloxyacetic acid

Base Information

• Chemical Name: cholest-5-en-3β-yloxyacetic acid
• CAS No.: 30656-77-0
• Molecular Formula: C₂₉H₄₈O₃
• Molecular Weight: 444.698
• Mol file: 30656-77-0.mol

Synonyms:cholest-5-en-3β-yloxyacetic acid

Chemical Property of cholest-5-en-3β-yloxyacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cholest-5-en-3β-yloxyacetic acid

There total 1 articles about cholest-5-en-3β-yloxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

cyclohexane (110-82-7,25012-93-5) + (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl 2-diazoacetate (85135-66-6) → cholesterol (57-88-5) + cholest-5-en-3β-yloxyacetic acid (30656-77-0) + cholesteryl formate (4351-55-7) + cholesteryl cyclohexylacetate (85135-67-7)

Guidance literature:

at 33 ℃; for 0.25h; Irradiation;

DOI:10.1021/ja00348a053

Reference yield: 65.0%

C24H39F3N2O3 (1263321-06-7) + cholest-5-en-3β-yloxyacetic acid (30656-77-0) → C53H85F3N2O5 (1263321-09-0)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In chloroform; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2010.11.046

Reference yield: 60.0%

C10H11F3N2O3 (1263321-07-8) + cholest-5-en-3β-yloxyacetic acid (30656-77-0) → C39H57F3N2O5 (1263321-10-3)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In chloroform; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2010.11.046

upstream raw materials:

cyclohexane

(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl 2-diazoacetate

Downstream raw materials:

(E)-2-[(3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yloxy]-3-(3-hydroxy-4-methoxy-phenyl)-acrylic acid

5-{(E)-2-Carboxy-2-[(3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yloxy]-vinyl}-2-hydroxy-benzoic acid

(E)-2-[(3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yloxy]-3-phenyl-acrylic acid

(E)-2-[(3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yloxy]-3-(4-hydroxy-phenyl)-acrylic acid