(1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane

Base Information

• Chemical Name: (1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane
• CAS No.: 716379-89-4
• Molecular Formula: C₂₇H₃₈BrOP
• Molecular Weight: 489.476
• Mol file: 716379-89-4.mol

Synonyms:(1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane

Chemical Property of (1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane

There total 1 articles about (1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine] (100281-23-0) + benzaldehyde (100-52-7) + methyl iodide (74-88-4) → (1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane (716379-89-4)

Guidance literature:

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine]; With n-butyllithium; In tetrahydrofuran; hexane; at -100 ℃; for 0.25h;

benzaldehyde; In tetrahydrofuran; hexane; at -100 - 20 ℃;

methyl iodide; In tetrahydrofuran; hexane; at 20 ℃; for 3h;

DOI:10.1021/jo0497407

Reference yield: 31.0%

(1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane (716379-89-4) → (Phenylethenyliden)(2,4,6-tri-tert-butylphenyl)phosphan (102150-16-3) + (E,E)-1,2-diphenyl-3,4-bis[(2,4,6-tri-tert-butylphenyl)phosphinidene]cyclobutene (165398-86-7,329235-77-0,106192-69-2) + 2,6-diphenyl-1,4-bis(2,4,6-tri-t-butylphenyl)-1,4-diphospha-1,4-dihydrofulvene

Guidance literature:

With tert.-butyl lithium; In tetrahydrofuran; pentane; at -100 - 20 ℃;

DOI:10.1021/jo0497407

Reference yield: 26.0%

(1-bromo-2-methoxy-2-phenyl-ethylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane (716379-89-4) → (methoxy-phenyl-vinylidene)-(2,4,6-tri-tert-butyl-phenyl)-phosphane

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1021/jo0497407

upstream raw materials:

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine]

benzaldehyde

methyl iodide

Downstream raw materials:

(Phenylethenyliden)(2,4,6-tri-tert-butylphenyl)phosphan

(E,E)-1,2-diphenyl-3,4-bis[(2,4,6-tri-tert-butylphenyl)phosphinidene]cyclobutene