C₃₅H₄₆O₄Si

Base Information

• Chemical Name: C₃₅H₄₆O₄Si
• CAS No.: 1453470-50-2
• Molecular Formula: C₃₅H₄₆O₄Si
• Molecular Weight: 558.833
• Mol file: 1453470-50-2.mol

Synonyms:C₃₅H₄₆O₄Si

Chemical Property of C₃₅H₄₆O₄Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₄₆O₄Si

There total 5 articles about C₃₅H₄₆O₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-(benzyloxy)-1-(dimethyl(phenyl)silyl)-4-phenylbutan-1-one (1453470-24-0) + 6-(tert-butyldimethylsilyloxy)-6-phenylhex-1-en-3-one (1453470-35-3) → C35H46O4Si (1453470-50-2)

Guidance literature:

With 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; isopropyl alcohol; at 75 ℃;

DOI:10.1021/ol402017x

Reference yield:

4-(benzyloxy)-1-morpholino-4-phenylbutan-1-one (1453470-18-2) → C35H46O4Si (1453470-50-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 3 h / -80 °C

2: 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran; isopropyl alcohol / 75 °C

With 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; isopropyl alcohol; 2: |Stetter 1,4-Dicarbonyl Synthesis;

DOI:10.1021/ol402017x

Reference yield:

benzyl bromide (100-39-0) → C35H46O4Si (1453470-50-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 5 - 8 h / 110 °C

1.2: 48 - 72 h / 20 °C / Darkness

2.1: tetrahydrofuran / 3 h / -80 °C

3.1: 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran; isopropyl alcohol / 75 °C

With 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; isopropyl alcohol; 3.1: |Stetter 1,4-Dicarbonyl Synthesis;

DOI:10.1021/ol402017x

upstream raw materials:

4-(benzyloxy)-1-morpholino-4-phenylbutan-1-one

4-(benzyloxy)-1-(dimethyl(phenyl)silyl)-4-phenylbutan-1-one

6-(tert-butyldimethylsilyloxy)-6-phenylhex-1-en-3-one

benzyl bromide