diethyl(4-(dimethylamino)benzoyl)phosphine sulfide

Base Information

• Chemical Name: diethyl(4-(dimethylamino)benzoyl)phosphine sulfide
• CAS No.: 1251445-57-4
• Molecular Formula: C₁₃H₂₀NOPS
• Molecular Weight: 269.348
• Mol file: 1251445-57-4.mol

Synonyms:diethyl(4-(dimethylamino)benzoyl)phosphine sulfide

Chemical Property of diethyl(4-(dimethylamino)benzoyl)phosphine sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl(4-(dimethylamino)benzoyl)phosphine sulfide

There total 2 articles about diethyl(4-(dimethylamino)benzoyl)phosphine sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

tetraethyldiphosphine disulfide (3790-23-6) + 4-(dimethylamino)benzoyl fluoride (108168-59-8) → diethyl(4-(dimethylamino)benzoyl)phosphine sulfide (1251445-57-4)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); bis(2-diphenylphosphinoethyl)phenylphosphine; for 4h; Inert atmosphere; Reflux;

DOI:10.1016/j.tetlet.2010.07.038

Reference yield: 53.0%

tetraethyldiphosphine disulfide (3790-23-6) + S-(4-methylphenyl) 4-(dimethylamino)benzenecarbothioate (1300197-12-9) → diethyl(4-(dimethylamino)benzoyl)phosphine sulfide (1251445-57-4) + 4-methylphenyl diethyldithiophosphinate (1300197-23-2)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); depe; In chlorobenzene; for 6h; Inert atmosphere; Reflux;

DOI:10.1016/j.tetlet.2011.02.112

Reference yield: 99.0%

diethyl(4-(dimethylamino)benzoyl)phosphine sulfide (1251445-57-4) + diphenyldisulfane (882-33-7) → phenyl diethyldithiophosphinate (88240-75-9) + S-phenyl 4-(dimethylamino)benzothioate (81157-19-9)

Guidance literature:

With hydridotetakis(triphenylphosphine)rhodium(I); 1,2-bis-(diphenylphosphino)ethane; In chlorobenzene; for 3h; Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2011.07.031

upstream raw materials:

tetraethyldiphosphine disulfide

4-(dimethylamino)benzoyl fluoride

S-(4-methylphenyl) 4-(dimethylamino)benzenecarbothioate

Downstream raw materials:

S-(4-methoxyphenyl) 4-(dimethylamino)benzenecarbothioate

diethyl(adamantan-1-ylcarbonyl)phosphine sulfide

diethyl(2-propylpentanoyl)phosphine sulfide

4-cyanophenyl 4-(dimethylamino)benzoate

Refernces

• 1、 Arisawa, Mieko,Yamada, Toru,Yamaguchi, Masahiko. "Synthesis of acylphosphine sulfides by rhodium-catalyzed reaction of acid fluorides and diphosphine disulfides". supporting information; experimental part. p. 4957 - 4958. Retrieved 2011/01/12.