(E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Base Information

Chemical Name:(E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester
CAS No.:224316-65-8
Molecular Formula:C₄₄H₅₈O₄
Molecular Weight:650.942
Hs Code.:

(E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Synonyms:(E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Suppliers and Price of (E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

There total 2 articles about (E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 49676-92-8
1,2-dibromocyclohex-1-ene

: 72526-00-2
(-)-8-phenylmenthyl acrylate

: (E)-3-Cyclohex-1-enyl-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

: 224316-65-8
(E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: With palladium diacetate; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; at 100 ℃; for 90h;
DOI:10.1002/(SICI)1099-0690(199808)1998:8<1521::AID-EJOC1521>3.0.CO;2-E

Reference yield:

: 98139-95-8
1,2-dibromo-1-chlorocyclohexane

: 224316-65-8
(E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / KOH / methanol / 3 h / Heating

2: 43 percent / PPh₃, Pd(OAc)2, NEt₃ / dimethylformamide / 90 h / 100 °C

With palladium diacetate; potassium hydroxide; triethylamine; triphenylphosphine; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/(SICI)1099-0690(199808)1998:8<1521::AID-EJOC1521>3.0.CO;2-E

Reference yield: 63.0%

: 224316-65-8
(E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

: (1R,2S,5R)-8-phenylmenthyl 3-(E)-<6-<2-(E)-(1R,4S,5R)-8-phenylmenthoxycarbonylethenyl>-7-oxabicyclo<4.1.0>hept-1-yl>acrylate

Guidance literature:: With disodium hydrogenphosphate; dihydrogen peroxide; urea; trifluoroacetic anhydride; In dichloromethane; acetonitrile; at 40 ℃; for 1h;
DOI:10.1021/jo981496u