3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole

Base Information

Chemical Name:3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole
CAS No.:1268376-06-2
Molecular Formula:C₂₁H₁₅FN₆OS
Molecular Weight:418.454
Hs Code.:

Synonyms:3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole

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Chemical Property of 3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole

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Technology Process of 3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole

There total 5 articles about 3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 78364-55-3
1-(6-fluorobenzo[d]thiazol-2-yl)hydrazine

: 56352-93-3
2-(4''-methoxyphenyl)-5-(3'-pyridinyl)-1,3,4-oxadiazole

: 1268376-06-2
3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole

Guidance literature:: With pyridine; Reflux;
DOI:10.1002/ardp.201000061

Reference yield:

: 348-40-3
2-amino-6-fluoro-1,3-benzothiazole

: 1268376-06-2
3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; hydrazine hydrate / water; ethylene glycol / Reflux

2: pyridine / Reflux

With pyridine; hydrogenchloride; hydrazine hydrate; In water; ethylene glycol;
DOI:10.1002/ardp.201000061

Reference yield:

: 371-40-4
4-fluoroaniline

: 1268376-06-2
3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-6-fluoro-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole

Guidance literature:: Multi-step reaction with 3 steps

1: ammonia; bromine; acetic acid

2: hydrogenchloride; hydrazine hydrate / water; ethylene glycol / Reflux

3: pyridine / Reflux

With pyridine; hydrogenchloride; ammonia; bromine; hydrazine hydrate; acetic acid; In water; ethylene glycol;
DOI:10.1002/ardp.201000061