(S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

Base Information

Chemical Name:(S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone
CAS No.:1380423-96-0
Molecular Formula:C₃₅H₄₃F₃O₃Si₂
Molecular Weight:624.891
Hs Code.:

Synonyms:(S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

Suppliers and Price of (S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

There total 5 articles about (S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1380423-87-9
(S)-2,2,3,3,9,9-hexamethyl-8,8-diphenyl-5-(prop-2-ynyl)-4,7-dioxa-3,8-disiladecane

: 23516-84-9
2,2,2-trifluoro-1-(4-iodophenyl)ethan-1-one

: 1380423-96-0
(S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 80 ℃; Inert atmosphere;

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 1380423-96-0
(S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide

1.2: 0 °C

2.1: n-butyllithium; boron trifluoride diethyl etherate / tetrahydrofuran / -78 °C / Inert atmosphere

3.1: 1H-imidazole / N,N-dimethyl-formamide / Inert atmosphere

3.2: Inert atmosphere

4.1: methanol; sodium methylate / methanol / 1 h / 20 °C / Inert atmosphere

5.1: copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 80 °C / Inert atmosphere

With 1H-imidazole; methanol; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; n-butyllithium; boron trifluoride diethyl etherate; sodium methylate; triethylamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

Reference yield:

: 895153-57-8
(S)-1-(tert-butyldiphenylsilyloxy)-5-(trimethylsilyl)pent-4-yn-2-ol

: 1380423-96-0
(S)-1-(4-(4-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy )pent-1-ynyl)phenyl)-2,2,2-trifluoroethanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / Inert atmosphere

1.2: Inert atmosphere

2.1: methanol; sodium methylate / methanol / 1 h / 20 °C / Inert atmosphere

3.1: copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 80 °C / Inert atmosphere

With 1H-imidazole; methanol; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium methylate; triethylamine; In methanol; N,N-dimethyl-formamide;