tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

Base Information

Chemical Name:tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate
CAS No.:1202036-32-5
Molecular Formula:C₁₇H₂₄N₄O₃
Molecular Weight:332.403
Hs Code.:

Synonyms:tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

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Chemical Property of tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

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Technology Process of tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

There total 1 articles about tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1202036-32-5
tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

Guidance literature:

Reference yield:

: 882672-05-1
6-bromo-2-chloroquinazoline

: 1202036-32-5
tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

: 1036756-33-8
tert-butyl 2-(3-(6-bromoquinazolin-2-ylamino)-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

Guidance literature:: In isopropyl alcohol; at 95 - 100 ℃;

Reference yield:

: 1202036-32-5
tert-butyl 2-(3-amino-5-(1-methyl-1H-pyrazol-4-yl)phenoxy)ethylcarbamate

: 1036749-89-9
N-(3-(2-aminoethoxy)-5-(1-methyl-1H-pyrazol-4-yl)phenyl)-6-ethynylquinazolin-2-amine

Guidance literature:: Multi-step reaction with 4 steps

1: isopropyl alcohol / 95 - 100 °C

2: copper(l) iodide; N-ethyl-N,N-diisopropylamine / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 95 °C

3: hydrogenchloride / 1,4-dioxane / 20 °C

4: sodium hydroxide / tetrahydrofuran; methanol / 20 °C

With hydrogenchloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine; sodium hydroxide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; 1,4-dioxane; methanol; N,N-dimethyl-formamide; isopropyl alcohol;