3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

Base Information

Chemical Name:3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester
CAS No.:256454-90-7
Molecular Formula:C₂₈H₃₀N₂O₄
Molecular Weight:458.557
Hs Code.:

Synonyms:3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

Suppliers and Price of 3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

There total 3 articles about 3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 256454-89-4
3-(4-Methoxycarbonyloxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

: 256454-90-7
3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

Guidance literature:: With ammonium hydroxide; In ethanol; at 20 ℃; for 4h;
DOI:10.1016/S0957-4166(99)00416-4

Reference yield:

: 501-97-3
4-hydroxyphenylpropionic acid

: 256454-90-7
3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / aq. NaOH / 20 °C

2: 58 percent / DCC; DMAP / CH₂Cl₂ / 4.5 h / 20 °C

3: 95 percent / 25 percent aq. NH₄OH / ethanol / 4 h / 20 °C

With dmap; ammonium hydroxide; sodium hydroxide; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; 1: Acylation / 2: Condensation / 3: ammonolysis;
DOI:10.1016/S0957-4166(99)00416-4

Reference yield:

: 134447-09-9
3-(-4-methoxycarbonyloxyphenyl)propionic acid

: 256454-90-7
3-(4-Hydroxy-phenyl)-propionic acid (S)-2,2-dimethyl-1-[6-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / DCC; DMAP / CH₂Cl₂ / 4.5 h / 20 °C

2: 95 percent / 25 percent aq. NH₄OH / ethanol / 4 h / 20 °C

With dmap; ammonium hydroxide; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; 1: Condensation / 2: ammonolysis;
DOI:10.1016/S0957-4166(99)00416-4