(2-Amino-6-(trifluoromethyl)phenyl)boronic acid

Base Information

Chemical Name:(2-Amino-6-(trifluoromethyl)phenyl)boronic acid
CAS No.:408359-16-0
Molecular Formula:C₇H₇BF₃NO₂
Molecular Weight:204.944
Hs Code.:
DSSTox Substance ID:DTXSID501228620

Synonyms:408359-16-0;(2-Amino-6-(trifluoromethyl)phenyl)boronic acid;[2-amino-6-(trifluoromethyl)phenyl]boronic acid;DTXSID501228620;Boronic acid, [2-amino-6-(trifluoromethyl)phenyl]-

Suppliers and Price of (2-Amino-6-(trifluoromethyl)phenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (2-Amino-6-(trifluoromethyl)phenyl)boronic acid

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:205.0521931
Heavy Atom Count:14
Complexity:200

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=C(C=CC=C1N)C(F)(F)F)(O)O

Technology Process of (2-Amino-6-(trifluoromethyl)phenyl)boronic acid

There total 3 articles about (2-Amino-6-(trifluoromethyl)phenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 408359-14-8
2-nitro-6-(trifluoromethyl)phenylboronic acid

: 408359-16-0
2-amino-6-(trifluoromethyl)phenylboronic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 1500.12 Torr;
DOI:10.1139/v01-156

Reference yield:

: 1423-27-4
2-(trifluoromethyl)phenylboronic acid

: 408359-16-0
2-amino-6-(trifluoromethyl)phenylboronic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 42 percent / 90 percent aq. HNO₃; H₂SO₄; urea / acetic anhydride / 0 - 20 °C

2: H₂ / 10 percent Pd/C / ethanol / 1500.12 Torr

With sulfuric acid; hydrogen; nitric acid; urea; palladium on activated charcoal; In ethanol; acetic anhydride;
DOI:10.1139/v01-156

Reference yield:

: 1333-74-0
hydrogen

: 408359-14-8
2-nitro-6-(trifluoromethyl)phenylboronic acid

: 408359-16-0
2-amino-6-(trifluoromethyl)phenylboronic acid

Guidance literature:: With palladium on activated charcoal; In ethanol; 10% Pd/C was added to soln. nitroboronic acid in EtOH and stirred under H2 (2 bar) overnight; soln. was filtered and concd. in vacuo;
DOI:10.1139/v01-156