(Hydroxyethyloxy)tri(Ethyloxy)octane

Base Information

• Chemical Name: (Hydroxyethyloxy)tri(Ethyloxy)octane
• CAS No.: 19327-39-0
• Molecular Formula: C₁₆H₃₄O₅
• Molecular Weight: 306.443
• Hs Code.: 2909499000
• European Community (EC) Number: 627-661-3
• DSSTox Substance ID: DTXSID3066479
• Nikkaji Number: J191.487A
• Wikidata: Q27095056
• Metabolomics Workbench ID: 56417
• Mol file: 19327-39-0.mol

Synonyms:19327-39-0;3,6,9,12-tetraoxaicosan-1-ol;(Hydroxyethyloxy)tri(Ethyloxy)octane;TETRAETHYLENE GLYCOL MONOOCTYL ETHER;3,6,9,12-Tetraoxaeicosan-1-ol;Tetraethylene glycol monoctyl ether;tetraethyleneglycol monooctyl ether;2-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]ethanol;C8E4;Octyl tetraethylene glycol ether;MFCD00043033;Octyltetraethyleneoxide;D06PVF;SCHEMBL185557;DTXSID3066479;CHEBI:41323;Tetraethylene glycol, octyl ether;AKOS027320403;DB04233;AS-59421;CS-0103110;FT-0755616;F14816;J-012514;Q27095056;Tetraethylene glycol monooctyl ether, liquid, >=98% (GC)

Chemical Property of (Hydroxyethyloxy)tri(Ethyloxy)octane

Chemical Property:

• Appearance/Colour: Cream to pale brown solid
• Vapor Pressure: 7.08E-08mmHg at 25°C
• Refractive Index: n20/D 1.449
• Boiling Point: 395 °C at 760 mmHg
• PKA: 14.36±0.10(Predicted)
• Flash Point: 192.7 °C
• PSA: 57.15000
• Density: 0.97 g/cm³
• LogP: 2.40560
• Storage Temp.: 2-8°C
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 18
• Exact Mass: 306.24062418
• Heavy Atom Count: 21
• Complexity: 178

Purity/Quality:

98%Min ^*data from raw suppliers

Tetraethylene glycol monooctyl ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCCCOCCOCCOCCOCCO
• Uses: Tetraethylene glycol monooctyl ether is a membrane solubilizing compound.

Technology Process of (Hydroxyethyloxy)tri(Ethyloxy)octane

There total 11 articles about (Hydroxyethyloxy)tri(Ethyloxy)octane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

→ 2-{2-[2-(2-Octyloxy-ethoxy)-ethoxy]-ethoxy}-ethanol (19327-39-0,798544-31-7,54141-05-8)

Guidance literature:

Reference yield:

Tetraethylene glycol (112-60-7) + 1-bromo-octane (111-83-1) → 2-{2-[2-(2-Octyloxy-ethoxy)-ethoxy]-ethoxy}-ethanol (19327-39-0,798544-31-7,54141-05-8)

Guidance literature:

Tetraethylene glycol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1.083h;

1-bromo-octane; In N,N-dimethyl-formamide; at 20 ℃; for 10h;

DOI:10.1016/j.tetlet.2013.09.004

Reference yield:

C16H30O5 (1351016-13-1) → 2-{2-[2-(2-Octyloxy-ethoxy)-ethoxy]-ethoxy}-ethanol (19327-39-0,798544-31-7,54141-05-8)

Guidance literature:

With palladium on activated charcoal; hydrogen; at 20 ℃; for 24h; under 15001.5 Torr; Autoclave;

DOI:10.1021/la203644k

upstream raw materials:

oxirane

triethylene glycol monooctyl ether

octanol

diethylene glycol octyl ether

Downstream raw materials:

pentaethylene glycol monooctyl ether

17-octyloxy-3,6,9,12,15-pentaoxa-heptadecan-1-ol

tetra(ethylene glycol) monoheptyl ether

Z-L-Phe-O-tetraethylene glycol-monooctylether

Refernces

• 1、 Liu, Wujun,Zhang, Yixin,Hou, Shuhua,Zhao, Zongbao Kent. "Synthesis of isoprenoid chain-contained chemical probes for an investigation of molecular interactions by using quartz crystal microbalance". supporting information. p. 6208 - 6210. Retrieved 2013/10/22.
• 2、 -. "Bna Conjugates and Methods of Use". Page/Page column 33. . Retrieved 2008/12/08.