diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

Base Information

Chemical Name:diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate
CAS No.:1355214-07-1
Molecular Formula:C₁₆H₂₀F₂NO₆P
Molecular Weight:391.308
Hs Code.:

Synonyms:diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

Suppliers and Price of diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

There total 4 articles about diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1355214-04-8
C₁₆H₂₁F₂INO₆P

: 1355214-07-1
diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Cooling;
DOI:10.1055/s-0030-1260239

Reference yield:

: 55-21-0,27208-38-4
benzamide

: 1355214-07-1
diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

Guidance literature:: Multi-step reaction with 4 steps

1: 1,2-dichloro-ethane / Cooling; Reflux

2: 1,2-dichloro-ethane / 20 °C

3: sodium dithionite; sodium hydrogencarbonate / water; acetonitrile / 3 h / 25 °C

4: sodium hydride / tetrahydrofuran / 20 °C / Inert atmosphere; Cooling

With sodium dithionite; sodium hydride; sodium hydrogencarbonate; In tetrahydrofuran; water; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1055/s-0030-1260239

Reference yield:

: 4461-33-0
benzoyl isocyanate

: 1355214-07-1
diethyl 2-(3-benzoyl-2-oxooxazolidin-4-yl)-1,1-difluoroethylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1: 1,2-dichloro-ethane / 20 °C

2: sodium dithionite; sodium hydrogencarbonate / water; acetonitrile / 3 h / 25 °C

3: sodium hydride / tetrahydrofuran / 20 °C / Inert atmosphere; Cooling

With sodium dithionite; sodium hydride; sodium hydrogencarbonate; In tetrahydrofuran; water; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1055/s-0030-1260239