rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine

Base Information

• Chemical Name: rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine
• CAS No.: 101938-44-7
• Molecular Formula: C₁₄H₁₆N₂O₂
• Molecular Weight: 244.293
• Mol file: 101938-44-7.mol

Synonyms:rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine

Chemical Property of rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine

There total 10 articles about rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

2,2'-dimethoxy-6,6'-dinitrobiphenyl (137465-71-5,137465-72-6,81540-51-4,1232237-01-2) → rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine (101938-44-7,151489-85-9)

Guidance literature:

2,2'-dimethoxy-6,6'-dinitrobiphenyl; With iron(III) chloride hexahydrate; pyrographite; In methanol; for 0.166667h; Reflux;

With hydrazine hydrate; In methanol; at 70 ℃; for 5.5h;

DOI:10.1039/b917554g

Reference yield:

2-iodo-3-nitrophenol (197243-48-4) → rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine (101938-44-7,151489-85-9)

Guidance literature:

Multi-step reaction with 3 steps

1: KOH

2: Cu / dimethylformamide / Heating

3: H₂ / Pd/C

With potassium hydroxide; hydrogen; copper; palladium on activated charcoal; In N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(96)01089-1

Reference yield:

2-iodo-1-methoxy-3-nitrobenzene (98991-08-3) → rac-6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine (101938-44-7,151489-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Cu / dimethylformamide / Heating

2: H₂ / Pd/C

With hydrogen; copper; palladium on activated charcoal; In N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(96)01089-1

upstream raw materials:

2,2'-dimethoxy-6,6'-dinitrobiphenyl

meta-nitrophenol

2-iodo-3-nitrophenol

2-iodo-1-methoxy-3-nitrobenzene

Downstream raw materials:

C₂₆H₂₂N₄O₆

(S)-6,6'-dimethoxybiphenyl-2,2'-diamine

6,6'-dimethoxy[1,1'-biphenyl]-2,2'-diamine