C₁₅H₂₂N₂O₂

Base Information

• Chemical Name: C₁₅H₂₂N₂O₂
• CAS No.: 1307856-70-7
• Molecular Formula: C₁₅H₂₂N₂O₂
• Molecular Weight: 262.352
• Mol file: 1307856-70-7.mol

Synonyms:C₁₅H₂₂N₂O₂

Chemical Property of C₁₅H₂₂N₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₂₂N₂O₂

There total 1 articles about C₁₅H₂₂N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-Amino-2-methyl-1-propanol (124-68-5) + (2R)-1[(R)-α-methylbenzyl]-2-aziridinecarboxylate ethyl ester (68820-82-6) → C15H22N2O2 (1307856-70-7)

Guidance literature:

2-Amino-2-methyl-1-propanol; With lanthanum(III) chloride; n-butyllithium; In cyclohexane; toluene; at 0 - 30 ℃; for 0.25h; Inert atmosphere;

(2R)-1[(R)-α-methylbenzyl]-2-aziridinecarboxylate ethyl ester; In cyclohexane; toluene; at 30 ℃; for 1h; Inert atmosphere;

DOI:10.1002/chem.201003424

Reference yield: 50.0%

C15H22N2O2 (1307856-70-7) → C15H20N2O (1307856-74-1)

Guidance literature:

With diethylamino-sulfur trifluoride; In dichloromethane; at -78 ℃; for 3h; Inert atmosphere;

DOI:10.1002/chem.201003424

Reference yield:

C15H22N2O2 (1307856-70-7) → C15H19(2)HN2O (1307856-78-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diethylamino-sulfur trifluoride / dichloromethane / 3 h / -78 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; cyclohexane / 0.25 h / -98 °C / Inert atmosphere

2.2: 1 h / -98 °C / Inert atmosphere

With n-butyllithium; diethylamino-sulfur trifluoride; In tetrahydrofuran; dichloromethane; cyclohexane;

DOI:10.1002/chem.201003424

upstream raw materials:

2-Amino-2-methyl-1-propanol

(2R)-1[(R)-α-methylbenzyl]-2-aziridinecarboxylate ethyl ester

Downstream raw materials:

C₁₅H₁₉⁽²⁾HN₂O

C₁₆H₂₂N₂O

C₁₇H₂₄N₂O

(1'R,2R)-butyl-1-(phenylethyl)aziridin-2-yl ketone