6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide

Base Information

• Chemical Name: 6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide
• CAS No.: 132735-22-9
• Molecular Formula: C₁₅H₁₅ClN₄*HI
• Molecular Weight: 414.676
• Mol file: 132735-22-9.mol

Synonyms:6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide

Chemical Property of 6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide

There total 4 articles about 6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

6-Chloro-2-ethylthio-1-methyl-4-phenyl-1H-1,4-dihydroquinazoline hydroiodide (132735-19-4) → 6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide (132735-22-9)

Guidance literature:

With hydrazine hydrate; In ethanol; for 4h; Heating;

Reference yield:

2-methylamino-5-chlorobenzhydrol (13386-35-1) → 6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide (132735-22-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / aq. HCl / 1.5 h / 80 °C

2: 90 percent / 3 h / Heating

3: 85 percent / N₂H₄*H₂O / ethanol / 4 h / Heating

With hydrazine hydrate; In hydrogenchloride; ethanol;

Reference yield:

6-Chloro-1-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydroquinazoline (26920-08-1) → 6-Chloro-2-hydrazino-1-methyl-4-phenyl-1,4-dihydroquinazoline hydroiodide (132735-22-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / 3 h / Heating

2: 85 percent / N₂H₄*H₂O / ethanol / 4 h / Heating

With hydrazine hydrate; In ethanol;

upstream raw materials:

6-Chloro-2-ethylthio-1-methyl-4-phenyl-1H-1,4-dihydroquinazoline hydroiodide

2-methylamino-5-chlorobenzhydrol

6-Chloro-1-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydroquinazoline

5-chloro-2-(methylamino)benzophenone

Downstream raw materials:

6-Chloro-1-methyl-2-<2-(2-nitrobenzylidene)-hydrazino>-4-phenyl-1H-1,4-dihydroquinazoline hydroiodide

7-Chlor-3,10-dimethyl-5-phenyl-5,10-dihydro<1,2,4>triazolo<3,4-b>chinazolin

6-Chloro-2-(2-ethylidenehydrazino)-1-methyl-4-phenyl-1H-1,4-dihydroquinazoline hydroiodide

7-Chlor-10-methyl-5-phenyl-3-thioxo-5,10-dihydro<1,2,4>triazolo<3,4-b>chinazolinhydroiodid