N-Ethyl-o-deuterobenzamide

Base Information

• Chemical Name: N-Ethyl-o-deuterobenzamide
• CAS No.: 87768-57-8
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 150.184
• Mol file: 87768-57-8.mol

Synonyms:N-Ethyl-o-deuterobenzamide

Chemical Property of N-Ethyl-o-deuterobenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Ethyl-o-deuterobenzamide

There total 14 articles about N-Ethyl-o-deuterobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

N,N-diethylbenzamide (1696-17-9) → 2-(diethylcarbamoyl)benzophenone (3034-28-4) + 2-deuterio-N,N-diethyl-benzamide (62924-91-8) + N-Ethyl-o-deuterobenzamide (87768-57-8)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.75h; Yields of byproduct given; N-ethylbenzamide, CH₃OD;

DOI:10.1016/S0040-4020(01)91916-7

Reference yield:

2-Bromo-N-ethylbenzamide (80031-02-3) → N-ethylbenzamide (614-17-5) + N-Ethyl-o-deuterobenzamide (87768-57-8)

Guidance literature:

With tert.-butyl lithium; In diethyl ether; for 0.5h; Yields of byproduct given;

DOI:10.1021/jo00078a007

Reference yield:

N-ethylbenzamide (614-17-5) → 2-(diethylcarbamoyl)benzophenone (3034-28-4) + 2-deuterio-N,N-diethyl-benzamide (62924-91-8) + N-Ethyl-o-deuterobenzamide (87768-57-8)

Guidance literature:

With deuteromethanol; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.75h; In the presence of N,N-diethylbenzamide; relative rates of metallation;

DOI:10.1016/S0040-4020(01)91916-7

upstream raw materials:

N,N-diethylbenzamide

N-ethylbenzamide

2-Bromo-N-ethylbenzamide

C₉H₉⁽²⁾HINO