3034-28-4Relevant articles and documents
Rapid synthesis of isoquinolinones by intramolecular coupling of amides and ketones
Wei, Wen-Tao,Liu, Yu,Ye, Lin-Miao,Lei, Rong-Hui,Zhang, Xue-Jing,Yan, Ming
supporting information, p. 817 - 824 (2015/02/19)
Amides and ketones were intramolecularly coupled in the presence of KOt-Bu/DMF. The reaction provided good yields of a variety of isoquinolinones. A reaction mechanism of radical addition and subsequent E2-elimination is proposed.
Application of directed orthometalation toward the synthesis of aryl siloxanes
Seganish, W. Michael,DeShong, Philip
, p. 6790 - 6795 (2007/10/03)
A selection of ortho-substituted aryl siloxanes have been prepared by directed orthometalation protocols. These siloxanes can be prepared in high yields and purity by use of a diverse selection of ortho-directing groups and electrophilic siloxane derivatives. The siloxanes are employed in palladium-catalyzed cross-coupling reactions with aryl bromides to generate unsymmetrical orthosubstituted biaryls in good to excellent yields.
Preparation of 3-Hydroxyindolin-1-ones and o-Acylbenzamides. A Study of Ring-Chain Tautomerism
Nishio, Takehiko,Yamamoto, Hiroshi
, p. 883 - 892 (2007/10/02)
3-Hydroxyisoindolinones (ring form) as well as their chain tautomers, o-acylbenzamides, were prepared from the reactions of 3-benzalphthalide 1, 3-halophthalides 3, and o-acylbenzoic acids 6 or their esters 7 with amines 2, and those of phthalimides 4 wit
