(E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene

Base Information

• Chemical Name: (E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene
• CAS No.: 1255763-09-7
• Molecular Formula: C₁₂H₆BrF₉
• Molecular Weight: 401.069
• Mol file: 1255763-09-7.mol

Synonyms:(E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene

Chemical Property of (E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene

There total 5 articles about (E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,3,4,4,5,5,6,6,6-Nonafluoro-1-hexene (19430-93-4) + 4-bromobenzenediazonium tetrafluoroborate (673-40-5) → (E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene (1255763-09-7)

Guidance literature:

With palladium diacetate; In methanol; at 20 - 40 ℃; Inert atmosphere;

DOI:10.1039/c0ob00564a

Reference yield: 72.0%

1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane (423-39-2) + 3-(4-bromophenyl)acrylic acid (1200-07-3) → (E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene (1255763-09-7)

Guidance literature:

With [2,2]bipyridinyl; copper(I) trifluoromethanesolfonate toluene complex; Dimethyl phosphite; In acetonitrile; at 80 ℃; for 72h; stereoselective reaction; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.6b02613

Reference yield:

1,4-bromoiodobenzene (589-87-7) + dimethyl(3,3,4,4,5,5,6,6,6-nonafluorohexen-1-yl)fluorosilane → (E)-1-bromo-4-(3,3,4,4,5,5,6,6,6-nonafluorohex-1-en-1-yl)benzene (1255763-09-7)

Guidance literature:

With tetrabutyl ammonium fluoride; palladium diacetate; In N,N-dimethyl-formamide; at 20 ℃; for 168h; Inert atmosphere;

DOI:10.1016/j.jfluchem.2012.03.007

upstream raw materials:

3,3,4,4,5,5,6,6,6-Nonafluoro-1-hexene

4-bromobenzenediazonium tetrafluoroborate

1,4-bromoiodobenzene

1,3-bis(1-iodo-3,3,4,4,5,5,6,6,6-nonafluorohexan-1-yl)tetramethyldisiloxane

Downstream raw materials:

bis[4-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)phenyl]phosphine oxide

(((acetylthio)methyl)bis(4-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)phenyl)phosphonio)trihydroborate

(bis(4-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)phenyl)phosphonio)trihydroborate