3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

Base Information

Chemical Name:3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose
CAS No.:250696-86-7
Molecular Formula:C₂₂H₃₄O₆Si
Molecular Weight:422.594
Hs Code.:

Synonyms:3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

Suppliers and Price of 3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

There total 7 articles about 3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 98-88-4
benzoyl chloride

: 189165-95-5
6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

: 250696-86-7
3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

Guidance literature:: With pyridine; at 20 ℃; for 4h;
DOI:10.1021/jm990486y

Reference yield: 87.0%

: 250696-99-2
Benzoic acid (3aR,5R,6R,6aR)-5-[(R)-2-(tert-butyl-dimethyl-silanyloxy)-1-(imidazole-1-carbothioyloxy)-ethyl]-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

: 250696-86-7
3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; for 3h; Heating;
DOI:10.1080/07328319908044857

Reference yield:

: 29474-73-5
(+)-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranos-3-yl benzoate

: 250696-86-7
3-O-benzoyl-6-O-(tert-butyldimethylsilyl)-5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose

Guidance literature:: Multi-step reaction with 4 steps

1: 76 percent / 0.4 percent HCl / acetonitrile; H₂O / 8 h / 20 °C

2: 92 percent / imidazole / dimethylformamide; CH₂Cl₂ / -15 - 0 °C

3: 89 percent / 1,2-dichloro-ethane / 4 h / Heating

4: 87 percent / n-Bu₃SnH; AIBN / toluene / 3 h / Heating

With 1H-imidazole; hydrogenchloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In dichloromethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene; acetonitrile; 1: Hydrolysis / 2: Silylation / 3: Esterification / 4: Reduction;
DOI:10.1080/07328319908044857