2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane

Base Information

• Chemical Name: 2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane
• CAS No.: 132929-45-4
• Molecular Formula: C₂₀H₁₉ClO₃S
• Molecular Weight: 374.888
• Mol file: 132929-45-4.mol

Synonyms:2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane

Chemical Property of 2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane

There total 5 articles about 2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Benzoic acid (1R,2S,4R)-1-(7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)methyl ester (132929-34-1,132929-35-2) + benzenesulfenyl chloride (931-59-9) → 2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane (132929-45-4)

Guidance literature:

In chloroform; at 0 ℃; for 48h;

DOI:10.1016/S0040-4020(01)81476-9

Reference yield:

(1RS,2SR,4RS)-7-oxabicyclo[2.2.1]hept-5-ene-2-methanol (89898-05-5,111080-27-4,112348-74-0,112348-87-5,133147-32-7) → 2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane (132929-45-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 0 °C

2: CHCl₃ / 0 °C

With pyridine; In chloroform;

DOI:10.1021/jo00093a024

Reference yield:

benzoyl chloride (98-88-4) → 2-endo-((Benzyloxy)methyl)-5-endo-chloro-6-exo-(phenylsulfenyl)-7-oxabicyclo<2.2.1>heptane (132929-45-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 0 °C

2: CHCl₃ / 0 °C

With pyridine; In chloroform;

DOI:10.1021/jo00093a024

upstream raw materials:

Benzoic acid (1R,2S,4R)-1-(7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)methyl ester

benzenesulfenyl chloride

(1RS,2SR,4RS)-7-oxabicyclo[2.2.1]hept-5-ene-2-methanol

benzoyl chloride