3-Chloro-N,N-bis(2-hydroxyethyl)aniline

Base Information

• Chemical Name: 3-Chloro-N,N-bis(2-hydroxyethyl)aniline
• CAS No.: 92-00-2
• Molecular Formula: C10H14 Cl N O2
• Molecular Weight: 215.68
• Hs Code.: 2922199090
• European Community (EC) Number: 202-115-3
• NSC Number: 58170
• UNII: EN37T6H6NK
• DSSTox Substance ID: DTXSID4026557
• Nikkaji Number: J78.146K
• Wikidata: Q27277254
• ChEMBL ID: CHEMBL3187164
• Mol file: 92-00-2.mol

Synonyms:92-00-2;3-Chloro-N,N-bis(2-hydroxyethyl)aniline;N,N-Bis(2-hydroxyethyl)-3-chloroaniline;2-[(3-chlorophenyl)(2-hydroxyethyl)amino]ethanol;N-(3-Chlorophenyl)diethanolamine;2,2'-(3-Chlorophenylimino)diethanol;2,2'-((3-Chlorophenyl)azanediyl)diethanol;Emery 5715;N-(m-Chlorophenyl)diethanolamine;(m-Chlorophenyl)diethanolamine;Emery 5717;Diethanolaminochlorobenzene;Ethanol, 2,2'-[(3-chlorophenyl)imino]bis-;2-[3-chloro-N-(2-hydroxyethyl)anilino]ethanol;Diethanolchloroanilide;N,N-Dihydroxyethyl-m-chloroaniline;N,N-Dihydroxyethyl-3-chloroaniline;m-Chloro-N,N-bis(2-hydroxyethyl)aniline;N,N-Bis(2-hydroxyethyl)chloroanilide;N,N-Di(hydroxyethyl)-m-chloroaniline;NSC 58170;Aniline, m-chloro-N,N-dihydroxyethyl-;Ethanol, 2,2'-(m-chloroanilino)bis-;2,2'-((m-Chlorophenyl)imino)diethanol;N,N-Diethanolanilide, 3-chloro-;2,2'-meta-(meta-Chlorophenylimino)diethanol;Ethanol, 2,2'-((m-chlorophenyl)imino)di-;Aniline, m-chloro-N,N-bis(2-hydroxyethyl)-;Ethanol, 2,2'-((3-chlorophenyl)imino)bis-;EINECS 202-115-3;2,2'-(m-Chlorophenylimino)diethanol;BRN 2806249;C10H14ClNO2;EN37T6H6NK;2,2'-[(3-chlorophenyl)imino]diethanol;2-[(3-chlorophenyl)(2-hydroxyethyl)amino]ethan-1-ol;AI3-12121;DTXSID4026557;NSC-58170;N,N-Bis(2-hydroxyethyl)-m-chloroaniline;N-(3-Chlorophenyl)-2,2'-iminodiethanol;N,N-Di(.beta.-hydroxyethyl)-m-chloroaniline;4-12-00-01141 (Beilstein Handbook Reference);2,2'-[(m-Chlorophenyl)imino]diethanol;m-Chlorophenyl diethanolamine;NN-Bis(2-hydroxyethyl)-m-chloroaniline;Emery-5715;Maybridge3_006251;Aniline,N-dihydroxyethyl-;UNII-EN37T6H6NK;Oprea1_420125;DTXCID906557;SCHEMBL2767092;CHEMBL3187164;Aniline,N-bis(2-hydroxyethyl)-;Ethanol,2'-(m-chloroanilino)bis-;HMS1448M03;NSC58170;Tox21_303219;2,2'-(3-chlorphenylimino)diethanol;CCG-51558;MFCD00002852;STK503331;AKOS005171561;CAS-92-00-2;Ethanol,2'-[(m-chlorophenyl)imino]di-;IDI1_017638;2,2'-(3-chlorophenylazanediyl)diethanol;3-Chloro-N,N-di(2-hydroxyethyl)aniline;N,N-Di(2-hydroxyethyl)-3-chloroaniline;NCGC00257111-01;Ethanol,2'-[(3-chlorophenyl)imino]bis-;LS-66608;B0490;CS-0316876;FT-0631444;N,N-BIS(HYDROXYETHYL)-3-CHLOROANILINE;D88659;A844121;2,2'-((3-Chlorophenyl)azanediyl)bis(ethan-1-ol);2,2'-((3-CHLOROPHENYL)IMINO)BIS(ETHANOL);N-(3-CHLORO-PHENYL)-2,2'-IMINO-DI-ETHANOL;SR-01000640851-1;W-100297;N,N-BIS(.BETA.-HYDROXYETHYL)-M-CHLOROANILINE;Q27277254

Chemical Property of 3-Chloro-N,N-bis(2-hydroxyethyl)aniline

Chemical Property:

• Appearance/Colour: pale yellow crystal
• Vapor Pressure: 4.97E-07mmHg at 25°C
• Melting Point: 84 - 86 C
• Refractive Index: 1.5500 (estimate)
• Boiling Point: 397.4 °C at 760 mmHg
• PKA: 14.25±0.10(Predicted)
• Flash Point: 194.2 °C
• PSA: 43.70000
• Density: 1.288 g/cm³
• LogP: 1.13100
• Solubility.: soluble in Methanol
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 215.0713064
• Heavy Atom Count: 14
• Complexity: 151

Purity/Quality:

99% ^*data from raw suppliers

N,N-Bis(2-Hydroxyethyl)-3-chloroaniline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)Cl)N(CCO)CCO
• Uses: N,N-Bis(2-Hydroxyethyl)-3-chloroaniline is a useful intermediate used in the synthesis of monoazo and bis azo dyes.

Technology Process of 3-Chloro-N,N-bis(2-hydroxyethyl)aniline

There total 2 articles about 3-Chloro-N,N-bis(2-hydroxyethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxirane (75-21-8,99932-75-9) + 3-chloro-aniline (108-42-9) → m-chloro-N,N-bis-β-hydroxyethylaniline (92-00-2)

Guidance literature:

DOI:10.1021/jo01064a039

Reference yield:

→ m-chloro-N,N-bis-β-hydroxyethylaniline (92-00-2)

Guidance literature:

3-Chlor-anilin, Aethylenoxyd, W., 50grad;

Reference yield: 92.0%

m-chloro-N,N-bis-β-hydroxyethylaniline (92-00-2) → (N-3-chlorophenyl)iminodiacetic acid (125340-66-1)

Guidance literature:

With C₂₄H₃₃IrN₄O₃; water; sodium hydroxide; for 18h; Reflux;

DOI:10.1002/cssc.202001052

upstream raw materials:

oxirane

3-chloro-aniline

Downstream raw materials:

3-chloro-N,N-bis-(2-hydroxy-ethyl)-4-(4-nitro-phenylazo)-aniline

3-chloro-N,N-bis-(2-vinyloxy-ethyl)-aniline

ethyl 5-<2-chloro-4-phenylazo>-2,4-bis(ethoxycarbonyl)-3-thiopheneacetate

N,N-bis-(2-ethoxy-ethyl)-3-chloro-aniline