2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid

Base Information

• Chemical Name: 2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid
• CAS No.: 102743-02-2
• Molecular Formula: C₁₆H₂₂N₂O₄
• Molecular Weight: 306.362
• Mol file: 102743-02-2.mol

Synonyms:2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid

Chemical Property of 2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid

There total 4 articles about 2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.6%

3,4-dimethyl-N-benzoyl-DL-glutamic anhydride (102743-18-0) + dimethyl amine (124-40-3) → 4-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid (102768-02-5) + 2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid (102743-02-2)

Guidance literature:

In tetrahydrofuran; at 25 ℃; for 3h;

Reference yield:

Glutamic acid (617-65-2,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → 2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid (102743-02-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / 1N NaOH / H₂O / 4 h / 15 - 20 °C

2: 82.5 percent / acetic anhydride / diisopropyl ether / 2 h / 70 °C

3: 57.6 percent / tetrahydrofuran / 3 h / 25 °C

With sodium hydroxide; acetic anhydride; In tetrahydrofuran; di-isopropyl ether; water;

Reference yield:

3,4-dimethyl-N-benzoyl-DL-glutamic acid (102743-17-9) → 2-(3,4-Dimethyl-benzoylamino)-4-dimethylcarbamoyl-butyric acid (102743-02-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82.5 percent / acetic anhydride / diisopropyl ether / 2 h / 70 °C

2: 57.6 percent / tetrahydrofuran / 3 h / 25 °C

With acetic anhydride; In tetrahydrofuran; di-isopropyl ether;

upstream raw materials:

3,4-dimethyl-N-benzoyl-DL-glutamic anhydride

dimethyl amine

Glutamic acid

3,4-dimethyl-N-benzoyl-DL-glutamic acid