9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine

Base Information

• Chemical Name: 9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine
• CAS No.: 83649-49-4
• Molecular Formula: C₃₀H₃₂N₆O₇
• Molecular Weight: 588.62
• Mol file: 83649-49-4.mol

Synonyms:9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine

Chemical Property of 9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine

There total 2 articles about 9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

adenine xyloside (524-69-6) → 9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine (83649-49-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 52 percent / triethyl orthoformate, 6 M HCl / dimethylformamide / 168 h / Ambient temperature

2: pyridine, dicyclohexylcarbodiimide / 96 h / Ambient temperature

With pyridine; hydrogenchloride; orthoformic acid triethyl ester; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;

DOI:10.1021/jm00356a010

Reference yield:

N-Cbz-L-Phe (1161-13-3) + 9-(3,5-O-isopropylidene-β-D-xylofuranosyl)adenine (7687-49-2) → 9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine (83649-49-4)

Guidance literature:

With pyridine; dicyclohexyl-carbodiimide; for 96h; Ambient temperature;

DOI:10.1021/jm00356a010

Reference yield: 37.0%

9-<2-O--3,5-O-isopropylidene-β-D-xylofuranosyl>adenine (83649-49-4) → 2'-O--9-β-D-xylofuranosyladenine (83649-43-8)

Guidance literature:

With acidic Dowex 50 WX₂; In ethanol; water; for 1h; Ambient temperature;

DOI:10.1021/jm00356a010

upstream raw materials:

N-Cbz-L-Phe

9-(3,5-O-isopropylidene-β-D-xylofuranosyl)adenine

adenine xyloside

Downstream raw materials:

2'-O--9-β-D-xylofuranosyladenine

(S)-2-Amino-3-phenyl-propionic acid (2R,3R,4S,5R)-2-(6-amino-purin-9-yl)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yl ester