ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride

Base Information

Chemical Name:ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride
CAS No.:1541198-78-0
Molecular Formula:C₁₄H₂₀ClNO₃*ClH
Molecular Weight:322.232
Hs Code.:

Synonyms:ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride

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Chemical Property of ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride

Chemical Property:

Purity/Quality:

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Technology Process of ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride

There total 6 articles about ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64-17-5
ethanol

: 1541198-76-8
3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propionic acid

: 1541198-78-0
ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride

Guidance literature:: With hydrogenchloride; for 2h; Reflux;

Reference yield:

: 1541198-74-6
2-(3-chloro-5-(1,3-dioxolan-2-yl)phenyl)propan-2-ol

: 1541198-78-0
ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / acetone / 1 h / 20 °C

2: ammonium acetate / isopropyl alcohol / 4 h / Reflux; Inert atmosphere

3: hydrogenchloride / 2 h / Reflux

With hydrogenchloride; ammonium acetate; toluene-4-sulfonic acid; In isopropyl alcohol; acetone;

Reference yield:

: 1541198-75-7
3-chloro-5-(2-hydroxypropan-2-yl)benzaldehyde

: 1541198-78-0
ethyl 3-amino-3-(3-chloro-5-(2-hydroxypropan-2-yl)phenyl)propanoate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / isopropyl alcohol / 4 h / Reflux; Inert atmosphere

2: hydrogenchloride / 2 h / Reflux

With hydrogenchloride; ammonium acetate; In isopropyl alcohol;