2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile

Base Information

• Chemical Name: 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile
• CAS No.: 142071-72-5
• Molecular Formula: C₃₂H₂₂N₄O
• Molecular Weight: 478.553

Synonyms:2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile

Chemical Property of 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile

There total 3 articles about 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-Phenacyl-3-cyanopyridiniumbromid (25357-46-4) + 1,1-dicyano-2-phenyl-4-phenyl-1,3-butadiene (68196-10-1) → 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile (142071-72-5)

Guidance literature:

With triethylamine; In methanol; at 20 ℃;

DOI:10.1007/BF00486803

Reference yield:

2-(1-phenylethylidene)propanedinitrile (5447-87-0) → 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile (142071-72-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / triethylamine / propan-2-ol / 0.5 h / Heating

2: 100 percent / triethylamine / methanol / 20 °C

With triethylamine; In methanol; isopropyl alcohol;

DOI:10.1007/BF00486803

Reference yield:

benzaldehyde (100-52-7) → 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile (142071-72-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / triethylamine / propan-2-ol / 0.5 h / Heating

2: 100 percent / triethylamine / methanol / 20 °C

With triethylamine; In methanol; isopropyl alcohol;

DOI:10.1007/BF00486803

upstream raw materials:

N-Phenacyl-3-cyanopyridiniumbromid

1,1-dicyano-2-phenyl-4-phenyl-1,3-butadiene

2-(1-phenylethylidene)propanedinitrile

benzaldehyde

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 142071-72-5 2-[((1R,2R,3S,8aR)-3-Benzoyl-6-cyano-2-phenyl-1,2,3,8a-tetrahydro-indolizin-1-yl)-phenyl-methylene]-malononitrile

Send

Send

Metric Ton KG G Pound L ML

Send

Send