1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate
CAS No.:1400589-53-8
Molecular Formula:C₁₇H₂₂ClN₅O₃
Molecular Weight:379.846
Hs Code.:

Synonyms:1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

Suppliers and Price of 1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-tert-Butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate 97%
5g
$ 950.00

Crysdot
(R)-tert-Butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate 97%
1g
$ 317.00

Ambeed
(R)-tert-Butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate 97%
1g
$ 75.00

Ambeed
(R)-tert-Butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate 97%
250mg
$ 31.00

Ambeed
(R)-tert-Butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate 97%
100mg
$ 16.00

Alichem
(R)-tert-Butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate
5g
$ 969.60

AK Scientific
(R)-Tert-butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate
250mg
$ 124.00

Total 4 raw suppliers

Chemical Property of 1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(R)-tert-Butyl2-((7-chloropyrido[4,3-b]pyrazin-5-ylamino)methyl)morpholine-4-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

There total 5 articles about 1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1174913-80-4
tert-butyl (2R)-2-(aminomethyl)morpholine-4-carboxylate

: 1379338-74-5
5,7-dichloropyrido[3,4-b]pyrazine

: 1400589-53-8
1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 130 ℃; for 0.666667h; microwave irradiation;

Reference yield:

: 101079-63-4
3,4-diamino-2,6-dichloropyridine

: 1400589-53-8
1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: tert-butyl alcohol / 1 h / Reflux

2: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 0.67 h / 130 °C / microwave irradiation

With N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; tert-butyl alcohol;

Reference yield:

: 2587-02-2
2,6-dichloro-[4]pyridylamine

: 1400589-53-8
1,1-dimethylethyl (2R)-2-{[(7-chloropyrido[3,4-b]pyrazin-5-yl)amino]methyl}-4-morpholinecarboxylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sulfuric acid / 0.08 h / 0 °C / Inert atmosphere

1.2: 1.08 h / 0 - 20 °C / Inert atmosphere

2.1: sulfuric acid / 2 h / 50 °C / Inert atmosphere

2.2: pH 10

3.1: ethanol; tin(ll) chloride / 6 h / 50 °C / Inert atmosphere

4.1: tert-butyl alcohol / 1 h / Reflux

5.1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 0.67 h / 130 °C / microwave irradiation

With ethanol; sulfuric acid; N-ethyl-N,N-diisopropylamine; tin(ll) chloride; In 1-methyl-pyrrolidin-2-one; tert-butyl alcohol;