5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine

Base Information

• Chemical Name: 5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine
• CAS No.: 1384216-46-9
• Molecular Formula: C₁₆H₂₆BNO₃
• Molecular Weight: 291.198
• Mol file: 1384216-46-9.mol

Synonyms:5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine

Chemical Property of 5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine

There total 1 articles about 5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-3-methoxybenzylamine (15184-99-3) + bis(pinacol)diborane (73183-34-3) → C16H26BNO3 (1384216-49-2) + 5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine (1384216-46-9) + C22H37B2NO5

Guidance literature:

With 2-(Aminomethyl)pyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In methyl cyclohexane; at 70 ℃; for 16h; Inert atmosphere;

DOI:10.1021/ol301635x

Reference yield: 52.0%

5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine (1384216-46-9) + aniline (62-53-3) → 2-((dimethylamino)methyl)-4-methoxy-N-phenylaniline

Guidance literature:

With oxygen; copper(II) acetate monohydrate; lithium carbonate; In acetonitrile; at 80 ℃; for 2h; chemoselective reaction; Schlenk technique; Molecular sieve;

DOI:10.1021/acs.joc.5b01074

Reference yield: 49.0%

5-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine (1384216-46-9) + 2,4,6-trimethylaniline (88-05-1) → N-(2-((dimethylamino)methyl)-4-methoxyphenyl)-2,4,6-trimethylaniline

Guidance literature:

With potassium fluoride; oxygen; copper(II) acetate monohydrate; In acetonitrile; at 80 ℃; for 2h; Schlenk technique; Molecular sieve;

DOI:10.1021/acs.joc.5b01074

upstream raw materials:

N,N-dimethyl-3-methoxybenzylamine

bis(pinacol)diborane