15184-99-3

Basic information

• Product Name: 3-METHOXY-N,N-DIMETHYLBENZYLAMINE
• Synonyms: 3-METHOXY-N,N-DIMETHYLBENZYLAMINE;(3-Methoxybenzyl)dimethylamine;3-Methoxy-N,N-dimethylbenzenemethanamine;BenzeneMethanaMine, 3-Methoxy-N,N-diMethyl-;1-(3-methoxyphenyl)-N,N-dimethylmethanamine
• CAS NO: 15184-99-3
• Molecular Formula: C₁₀H₁₅NO
• Molecular Weight: 165.23
• Product Categories: Amines;C9 to C10;Nitrogen Compounds
• Mol File: 15184-99-3.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 105 °C13 mm Hg(lit.)
• Flash Point: 205 °F
• Appearance: Colorless/Liquid
• Density: 0.984 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0885mmHg at 25°C
• Refractive Index: n20/D 1.514(lit.)
• PKA: 8.88±0.28(Predicted)
• CAS DataBase Reference: 3-METHOXY-N,N-DIMETHYLBENZYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-N,N-DIMETHYLBENZYLAMINE(15184-99-3)
• EPA Substance Registry System: 3-METHOXY-N,N-DIMETHYLBENZYLAMINE(15184-99-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 15184-99-3(Hazardous Substances Data)

Usage

General Description

3-Methoxy-N,N-dimethylbenzylamine is a chemical compound with the molecular formula C11H17NO. It is an amine and belongs to the class of organic compounds known as alkyl aryl ethers. 3-METHOXY-N,N-DIMETHYLBENZYLAMINE is commonly used as a reagent in organic synthesis and as an intermediate for the production of pharmaceuticals and other organic compounds. It is not known to occur naturally and is primarily synthesized in laboratory settings. 3-Methoxy-N,N-dimethylbenzylamine is a clear, colorless liquid with a characteristic amine odor and is soluble in organic solvents such as ethanol and ether. It is important to handle and store this chemical compound with proper care and caution due to its potential health hazards and flammability.

InChI:InChI=1/C10H15NO/c1-11(2)8-9-5-4-6-10(7-9)12-3/h4-7H,8H2,1-3H3

Upstream product

• 124-40-3 dimethyl amine 
• 874-98-6 1-bromomethyl-3-methoxybenzene 
• 7290-99-5 N,N-dimethyl-m-methoxybenzamide 
• 591-31-1 3-methoxy-benzaldehyde 
• 824-98-6 m-methoxybenzyl chloride 
• 67-56-1 methanol 
• 1527-89-5 3-methoxybenzonitrile 
• 6971-51-3 3-methoxybenzyl alcohol 
• 586-38-9 3-Methoxybenzoic acid 
• 506-59-2 N,N-dimethylammonium chloride 
• 50-00-0 formaldehyd 
• 5071-96-5 3-METHOXYBENZYLAMINE 
• 1711-05-3 m-anisoyl chloride 
• 78358-11-9 methanesulfonic acid 3-methoxy-benzyl ester 

Downstream Products

• 61186-04-7 3-Dimethylaminomethyl-phenol; hydrobromide 
• 591-31-1 3-methoxy-benzaldehyde 
• 91127-29-6 Methyl 6-<(N,N-dimethylamino)methyl>-2-methoxybenzoate 
• 97582-08-6 1-(N,N-dimethylamino)methyl-3-methoxy-2-propylbenzene 
• 97582-10-0 3-methoxy-N,N-dimethyl-2-(2-methylpropyl)benzenemethanamine 
• 119018-65-4 N,N-dimethyl-2-phenylthio-3-methoxy-benzylamine 
• 179675-99-1 (C₆H₃(CH₂N(CH₃)2)(OCH₃))HgCl 
• 1073268-78-6 C₂₀H₂₈N₂O₂Se₂ 
• 60760-04-5 3-[(N,N-dimethylamino)methyl]phenol 
• 1416982-12-1 1-(3-methoxyphenyl)-N,N,N-trimethylmethanaminium trifluoromethanesulfonate 

Relevant articles and documents

Electrochemical Dehydrogenative Imidation of N-Methyl-Substituted Benzylamines with Phthalimides for the Direct Synthesis of Phthalimide-Protected gem-Diamines

A general and green electrochemical dehydrogenative method for the imidation of N-methyl benzylamines with phthalimides with excellent regioselectivities is reported for the first time. This operationally simple method offers a valuable tool to obtain str

Lewis Acid-Catalyzed Reductive Amination of Aldehydes and Ketones with N,N-Dimethylformamide as Dimethylamino Source, Reductant and Solvent

A practical zinc acetate dihydrate-catalyzed reductive amination of various carbonyl compounds with N,N-dimethylformamide (DMF) as dimethylamino (Me2N) source, reductant and solvent has been developed. This reaction shows broad substrate scope,

Dual antitumor and antiangiogenic activity of organoplatinum(II) complexes

A library of over 20 cycloplatinated compounds of the type [Pt(dmba-R)LCl] (dmba-R = C,N-dimethylbenzylamine-like ligand; R being MeO, Me, H, Br, F, CF3, and NO2 substituents in the R5 or R4 position of the phenyl ring; L = DMSO and P(C6H4CF3-p)3) has been prepared. All compounds are active in both human ovarian carcinoma A2780 cells and cisplatin-resistant A2780cisR cells, with most of the DMSO platinum complexes exhibiting IC50 values in the submicromolar range in the A2780 cell line. Interestingly, DMSO platinum complexes show low cytotoxicity in the nontumorigenic kidney cell line BGM and therefore high selectivity factors SF. In addition, some of the DMSO platinum complexes effectively inhibit angiogenesis in the human umbilical vein endothelial cell line EA.hy926. These are the first platinum(II) complexes reported to inhibit angiogenesis at a close concentration to their IC50 in A2780 cells, turning them into dual cytotoxic and antiangiogenic compounds.