(+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate

Base Information

• Chemical Name: (+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate
• CAS No.: 1185040-28-1
• Molecular Formula: C₁₀H₁₄O₄
• Molecular Weight: 198.219
• Mol file: 1185040-28-1.mol

Synonyms:(+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate

Chemical Property of (+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate

There total 2 articles about (+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

propan-1-ol (71-23-8) + carbon monoxide (201230-82-2) + cis-(1S,2S)-1,2-dihydroxy-3-iodocyclohexa-3,5-diene (138769-92-3) → (+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate (1185040-28-1)

Guidance literature:

With palladium diacetate; triethylamine; triphenylphosphine; at 40 ℃; under 760.051 Torr;

DOI:10.1039/c4ob01417k

Reference yield:

propyl benzoate (2315-68-6) → (+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate (1185040-28-1)

Guidance literature:

With Escherichia coli JM 109(pDTG 601) strain; Inert atmosphere; Enzymatic reaction;

DOI:10.1039/b902577b

Reference yield: 91.0%

(+)-n-propyl (5S,6R)-5,6-dihydroxycyclohexa-1,3-dienecarboxylate (1185040-28-1) → C10H16O4 (1185040-41-8)

Guidance literature:

With potassium diazodicarboxylate; acetic acid; In methanol; at -15 - 20 ℃; chemoselective reaction; Inert atmosphere;

DOI:10.1039/b902577b

upstream raw materials:

propyl benzoate

propan-1-ol

carbon monoxide

cis-(1S,2S)-1,2-dihydroxy-3-iodocyclohexa-3,5-diene

Downstream raw materials:

C₁₀H₁₆O₄