C₃₅H₄₃BrO₇Si

Base Information

• Chemical Name: C₃₅H₄₃BrO₇Si
• CAS No.: 532393-12-7
• Molecular Formula: C₃₅H₄₃BrO₇Si
• Molecular Weight: 683.712
• Mol file: 532393-12-7.mol

Synonyms:C₃₅H₄₃BrO₇Si

Chemical Property of C₃₅H₄₃BrO₇Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₄₃BrO₇Si

There total 9 articles about C₃₅H₄₃BrO₇Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-3-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-4-methoxyphenol (347840-54-4) → C35H43BrO7Si (532393-12-7)

Guidance literature:

Multi-step reaction with 8 steps

1.1: K₂CO₃ / dimethylformamide / 2.5 h / 20 °C

2.1: 2 h / 180 °C

2.2: 70 percent / PhI(OAc)2 / 0.33 h / 20 °C

3.1: 90 percent / pyridinium p-toluenesulfonate / benzene / 0.33 h / 80 °C

4.1: 62 percent / OsO₄; NaIO₄ / tetrahydrofuran; H₂O; toluene / 1.5 h / 20 °C

5.1: 76 percent / BH₃*t-BuNH₂ / methanol; H₂O; tetrahydrofuran / 0.33 h / 0 °C

6.1: Ph₃COOH; L-DIPT; 4A molecular sieve / toluene; tetrahydrofuran / 50 h / -40 °C

7.1: Dess-Martin periodinane / CH₂Cl₂ / 0.58 h / 20 °C

8.1: 270 mg / CH₂Cl₂ / 4 h / -78 - 5 °C

With sodium periodate; osmium(VIII) oxide; L-(+)-diisopropyl tartrate; trityl hydroperoxide; 4 A molecular sieve; N-tert-butylaminoborane; pyridinium p-toluenesulfonate; potassium carbonate; Dess-Martin periodane; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; benzene; 2.1: Claisen rearrangement / 4.1: Lemieux-Johnson oxidation / 7.1: Dess-Martin oxidation;

DOI:10.1021/ja021396c

Reference yield:

[[2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-methoxyphenyl]methoxy](1,1-dimethylethyl)diphenylsilane (347840-66-8) → C35H43BrO7Si (532393-12-7)

Guidance literature:

Multi-step reaction with 9 steps

1.1: TBAF / tetrahydrofuran / 0.17 h / 0 °C

2.1: K₂CO₃ / dimethylformamide / 2.5 h / 20 °C

3.1: 2 h / 180 °C

3.2: 70 percent / PhI(OAc)2 / 0.33 h / 20 °C

4.1: 90 percent / pyridinium p-toluenesulfonate / benzene / 0.33 h / 80 °C

5.1: 62 percent / OsO₄; NaIO₄ / tetrahydrofuran; H₂O; toluene / 1.5 h / 20 °C

6.1: 76 percent / BH₃*t-BuNH₂ / methanol; H₂O; tetrahydrofuran / 0.33 h / 0 °C

7.1: Ph₃COOH; L-DIPT; 4A molecular sieve / toluene; tetrahydrofuran / 50 h / -40 °C

8.1: Dess-Martin periodinane / CH₂Cl₂ / 0.58 h / 20 °C

9.1: 270 mg / CH₂Cl₂ / 4 h / -78 - 5 °C

With sodium periodate; osmium(VIII) oxide; L-(+)-diisopropyl tartrate; trityl hydroperoxide; 4 A molecular sieve; N-tert-butylaminoborane; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; potassium carbonate; Dess-Martin periodane; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; benzene; 3.1: Claisen rearrangement / 5.1: Lemieux-Johnson oxidation / 8.1: Dess-Martin oxidation;

DOI:10.1021/ja021396c

Reference yield:

[[2-bromo-6-methoxy-3-(2-propenyloxy)phenyl]methoxy](1,1-dimethylethyl)diphenylsilane (311312-50-2) → C35H43BrO7Si (532393-12-7)

Guidance literature:

Multi-step reaction with 7 steps

1.1: 2 h / 180 °C

1.2: 70 percent / PhI(OAc)2 / 0.33 h / 20 °C

2.1: 90 percent / pyridinium p-toluenesulfonate / benzene / 0.33 h / 80 °C

3.1: 62 percent / OsO₄; NaIO₄ / tetrahydrofuran; H₂O; toluene / 1.5 h / 20 °C

4.1: 76 percent / BH₃*t-BuNH₂ / methanol; H₂O; tetrahydrofuran / 0.33 h / 0 °C

5.1: Ph₃COOH; L-DIPT; 4A molecular sieve / toluene; tetrahydrofuran / 50 h / -40 °C

6.1: Dess-Martin periodinane / CH₂Cl₂ / 0.58 h / 20 °C

7.1: 270 mg / CH₂Cl₂ / 4 h / -78 - 5 °C

With sodium periodate; osmium(VIII) oxide; L-(+)-diisopropyl tartrate; trityl hydroperoxide; 4 A molecular sieve; N-tert-butylaminoborane; pyridinium p-toluenesulfonate; Dess-Martin periodane; In tetrahydrofuran; methanol; dichloromethane; water; toluene; benzene; 1.1: Claisen rearrangement / 3.1: Lemieux-Johnson oxidation / 6.1: Dess-Martin oxidation;

DOI:10.1021/ja021396c

upstream raw materials:

tert-butyl 2-(triphenylphosphoranylidene)propionate

2-bromo-3-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-4-methoxyphenol

[[2-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-6-methoxyphenyl]methoxy](1,1-dimethylethyl)diphenylsilane

[[2-bromo-6-methoxy-3-(2-propenyloxy)phenyl]methoxy](1,1-dimethylethyl)diphenylsilane

Downstream raw materials:

C₄₂H₅₆O₇Si