(3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol

Base Information

Chemical Name:(3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol
CAS No.:36640-55-8
Molecular Formula:C₁₆H₁₃BrN₂O
Molecular Weight:329.196
Hs Code.:
DSSTox Substance ID:DTXSID301233663
ChEMBL ID:CHEMBL1575729
Mol file:36640-55-8.mol

Synonyms:(3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol;36640-55-8;[3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl]methanol;MLS000974447;SCHEMBL3407292;CHEMBL1575729;DTXSID301233663;HMS2834J11;AKOS001010731;SMR000496811;EU-0075684;SR-01000469717;3-(4-Bromophenyl)-1-phenyl-1H-pyrazole-4-methanol;SR-01000469717-1;Z56787621;F0915-1534

Suppliers and Price of (3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(3-(4-BROMOPHENYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL Aldrich
250mg
$ 57.00

American Custom Chemicals Corporation
(3-(4-BROMOPHENYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
(3-(4-BROMOPHENYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
(3-(4-BROMOPHENYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL 95.00%
1G
$ 1030.84

Total 5 raw suppliers

Chemical Property of (3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:328.02113
Heavy Atom Count:20
Complexity:301

Purity/Quality:

99% ^*data from raw suppliers

(3-(4-BROMOPHENYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=C(C=C3)Br)CO

Technology Process of (3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol

There total 6 articles about (3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 36640-41-2
3-(4-bromophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde

: 36640-55-8
(3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 1h;
DOI:10.1023/A:1016346528487

Reference yield:

: 99-90-1
para-bromoacetophenone

: 36640-55-8
(3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid

2: trichlorophosphate / 2 h / 90 °C

3: sodium tetrahydroborate / ethanol / 1 h / 20 °C

With sodium tetrahydroborate; acetic acid; trichlorophosphate; In ethanol; 2: |Vilsmeier-Haack Formylation;
DOI:10.1021/acs.jmedchem.7b01562

Reference yield:

: (1E)-1-[1-(4-bromophenyl)ethylidene]-2-phenylhydrazine

: 36640-55-8
(3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / 5 h / 0 - 20 °C / Inert atmosphere; Reflux

2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / Reflux

With lithium aluminium tetrahydride; trichlorophosphate; In tetrahydrofuran;
DOI:10.1021/jm3010543