Cefpodoxime Proxetil,(S)

Base Information

Chemical Name:Cefpodoxime Proxetil,(S)
CAS No.:80210-62-4
Molecular Formula:C15H17N5O6S2
Molecular Weight:427.462
Hs Code.:
European Community (EC) Number:685-334-0
Wikipedia:Cefpodoxime
NCI Thesaurus Code:C65305
RXCUI:20489
Mol file:80210-62-4.mol

Synonyms:cefpodoxime;R 3746;R 3763;R-3746;R-3763;RU 51746;RU-51746;U 76253A;U-76,253A

Suppliers and Price of Cefpodoxime Proxetil,(S)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CefpodoximeAcid
50mg
$ 155.00

Sigma-Aldrich
Cefpodoxime VETRANAL
25mg
$ 64.70

Medical Isotopes, Inc.
CefpodoximeAcid
5 mg
$ 950.00

Matrix Scientific
Cefpodoxime 95+%
1g
$ 1647.00

Matrix Scientific
Cefpodoxime 95+%
250mg
$ 742.00

Chemenu
(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid 95%
1g
$ 320.00

Cayman Chemical
Cefpodoxime (free acid) ≥95%
25mg
$ 53.00

Cayman Chemical
Cefpodoxime (free acid) ≥95%
10mg
$ 25.00

Cayman Chemical
Cefpodoxime (free acid) ≥95%
50mg
$ 99.00

Cayman Chemical
Cefpodoxime (free acid) ≥95%
100mg
$ 173.00

Total 72 raw suppliers

Chemical Property of Cefpodoxime Proxetil,(S)

Chemical Property:

Appearance/Colour:off-white solid
Melting Point:200-202 °C
Refractive Index:1.78
PKA:2.77±0.50(Predicted)
PSA：209.98000
Density:1.785 g/cm³
LogP:0.37080
Storage Temp.:-20°C Freezer
Sensitive.:Light Sensitive
Solubility.:Soluble in DMSO
XLogP3:-1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:7
Exact Mass:427.06202563
Heavy Atom Count:28
Complexity:744

Purity/Quality:

99% ^*data from raw suppliers

CefpodoximeAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 42/43
Safety Statements: 22-36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCC1=C(N2C(C(C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O
Isomeric SMILES:COCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)C(=NOC)C3=CSC(=N3)N)SC1)C(=O)O
Uses A metabolite of Cefpodoxime Proxetil. An antibacterial. A metabolite of Cefpodoxime Proxetil (C243860). An antibacterial. Cefpodoxime Proxetil metabolite antibiotic
Clinical Use Cefpodoxime has been used principally for the treatment of upper and lower respiratory tract infections in children and adults.

Technology Process of Cefpodoxime Proxetil,(S)

There total 11 articles about Cefpodoxime Proxetil,(S) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.86%

: 80756-85-0
(Z)-S-benzo[d]thiazol-2-yl 2-(2-aminothiazol-4-yl)-2-(methoxyimino)ethanethioate

: 24701-69-7
(6R,7R)-7-amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

: 80210-62-4
cefpodoxime

Guidance literature:: With triethylamine; In tetrahydrofuran; at -5 - 5 ℃; for 2h;

Reference yield: 82.2%

: 124-41-4
sodium methylate

: 75994-59-1
(Z)-α-(methoxyimino)-2-amino-4-thiazoleacetyl chloride

: 7-amino-3-chloromethyl-3-cephem-4-carboxylic acid

: 80210-62-4
cefpodoxime

Guidance literature:: sodium methylate; 7-amino-3-chloromethyl-3-cephem-4-carboxylic acid; With benzyltrihexylammonium chloride; potassium iodide; In dimethyl sulfoxide; at 15 ℃; for 8h;

(Z)-α-(methoxyimino)-2-amino-4-thiazoleacetyl chloride; In dimethyl sulfoxide; at 10 ℃; for 4h; Temperature; Solvent; Reagent/catalyst;

Reference yield:

: 959246-33-4
(benzothiazol-2-yl)-2-(2-aminothiazol-4-yl)-Z-2-methoxyimino-thioacetate

: 24701-69-7
(6R,7R)-7-amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

: 80210-62-4
cefpodoxime

Guidance literature:: (benzothiazol-2-yl)-2-(2-aminothiazol-4-yl)-Z-2-methoxyimino-thioacetate; (6R,7R)-7-amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; With triethylamine; In methanol; water; at 15 - 20 ℃;

With sulfuric acid; In methanol; water;