(2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

Base Information

Chemical Name:(2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine
CAS No.:130625-69-3
Molecular Formula:C₁₅H₁₉N₃O₆
Molecular Weight:337.332
Hs Code.:

Synonyms:(2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

Suppliers and Price of (2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

Chemical Property:

Purity/Quality:

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Technology Process of (2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

There total 3 articles about (2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 506-59-2
N,N-dimethylammonium chloride

: 96034-57-0
(2S,4R)-4-Hydroxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine-2-carboxylic acid

: 130625-69-3
(2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

Guidance literature:: With isopropyl chloroformate; triethylamine; In dichloromethane; at -10 - 0 ℃; for 2h;

Reference yield:

: 51-35-4,30724-02-8
4R-4-hydroxyproline

: 130625-69-3
(2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water / 0 - 5 °C

1.2: 0 - 5 °C

1.3: 0 - 5 °C

2.1: triethylamine; isopropyl chloroformate / dichloromethane / -30 - -20 °C

With isopropyl chloroformate; triethylamine; sodium hydroxide; In dichloromethane; water;

Reference yield:

: 4457-32-3
4-nitrobenzyl chloroformate

: 130625-69-3
(2S,4R)-1-p-Nitrobenzyloxycarbonyl-2-dimethylaminocarbonyl-4-hydroxypyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water / 0 - 5 °C

1.2: 0 - 5 °C

1.3: 0 - 5 °C

2.1: triethylamine; isopropyl chloroformate / dichloromethane / -30 - -20 °C

With isopropyl chloroformate; triethylamine; sodium hydroxide; In dichloromethane; water;