methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

Base Information

Chemical Name:methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate
CAS No.:910040-99-2
Molecular Formula:C₂₈H₃₀N₂O₄S
Molecular Weight:490.623
Hs Code.:

Synonyms:methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

Suppliers and Price of methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

There total 4 articles about methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 910040-98-1
(2S)-6-(N,N-dibenzylamino)-2-(para-toluenesulfonylamino)-hex-4-ynoic acid

: 910040-99-2
methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

Guidance literature:: In tetrahydrofuran; diethyl ether; at 0 ℃;
DOI:10.1039/b605026n

Reference yield:

: 68452-41-5
N,N-dibenzylpropargylamine

: 910040-99-2
methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / hexane; tetrahydrofuran / 0.5 h / 0 °C

1.2: 61 percent / hexane; tetrahydrofuran / 3.5 h / 0 °C

2.1: 75 percent / diethyl ether; tetrahydrofuran / 0 °C

With n-butyllithium; In tetrahydrofuran; diethyl ether; hexane;
DOI:10.1039/b605026n

Reference yield:

: 100-39-0
benzyl bromide

: 910040-99-2
methyl (2S)-6-(N,N-dibenzylamine)-2-(para-toluenesulfonylamino)-hex-4-ynoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 71 percent / aq. Na₂CO₃ / CH₂Cl₂ / 4 h / Heating

2.1: n-BuLi / hexane; tetrahydrofuran / 0.5 h / 0 °C

2.2: 61 percent / hexane; tetrahydrofuran / 3.5 h / 0 °C

3.1: 75 percent / diethyl ether; tetrahydrofuran / 0 °C

With n-butyllithium; sodium carbonate; In tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1039/b605026n