1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline

Base Information

Chemical Name:1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline
CAS No.:115848-91-4
Molecular Formula:C₂₄H₂₇ClN₄O₂
Molecular Weight:438.957
Hs Code.:

Synonyms:1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline

Chemical Property:

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Technology Process of 1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline

There total 6 articles about 1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 64-19-7,77671-22-8
acetic acid

: 115848-83-4
N-{4-[(E)-3-(4-Chloro-phenyl)-acryloyl]-phenyl}-2-piperidin-1-yl-acetamide

: 115848-91-4
1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline

Guidance literature:: With hydrazine hydrate; In acetic acid; for 10h; Heating;

Reference yield:

: 38283-38-4
4-(2-chloroacetamido)acetophenone

: 115848-91-4
1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent

2: 69 percent / 4percent aq. KOH / ethanol

3: 35 percent / hydrazine hydrate / acetic acid / 10 h / Heating

With potassium hydroxide; hydrazine hydrate; In ethanol; acetic acid;

Reference yield:

: 110-89-4
piperidine

: 115848-91-4
1-acetyl-5-(4-chlorophenyl)-3-(4'-piperidinoacetamidophenyl)-2-pyrazoline

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent

2: 69 percent / 4percent aq. KOH / ethanol

3: 35 percent / hydrazine hydrate / acetic acid / 10 h / Heating

With potassium hydroxide; hydrazine hydrate; In ethanol; acetic acid;