Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

Base Information

Chemical Name:Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate
CAS No.:162613-19-6
Molecular Formula:C₃₁H₃₄O₈S
Molecular Weight:566.672
Hs Code.:

Synonyms:Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

Suppliers and Price of Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

There total 6 articles about Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 100-07-2
4-methoxy-benzoyl chloride

: 162613-17-4
Methyl (ethyl 3,4-di-O-benzyl-1-thio-β-D-glucopyranosid)uronate

: 162613-19-6
Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

Guidance literature:: With pyridine; at 65 ℃; for 20h;
DOI:10.1021/jo00112a046

Reference yield:

: 141810-60-8
ethyl 3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-glucopyranoside

: 162613-19-6
Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

Guidance literature:: Multi-step reaction with 6 steps

1: 88 percent / pyridine / 2 h

2: 68 percent / AlCl₃, BH₃-Me₃N, 4 Angstroem molecular sieves / diethyl ether; CH₂Cl₂ / 1 h / 0 °C

3: pyridine, TFA, DCC / dimethylsulfoxide / Ambient temperature

4: PDC / dimethylformamide / Ambient temperature

5: 70 percent / MeONa / methanol / 24 h

6: 86 percent / pyridine / 20 h / 65 °C

With pyridine; dipyridinium dichromate; aluminium trichloride; trimethylamine-borane; 4 A molecular sieve; sodium methylate; dicyclohexyl-carbodiimide; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/jo00112a046

Reference yield:

: 162681-47-2
ethyl 2-O-acetyl-3-O-benzyl-4,6-O-benzylidene-1-thio-β-D-glucopyranoside

: 162613-19-6
Methyl (ethyl 3,4-di-O-benzyl-2-O-(p-methoxybenzoyl)-1-thio-β-D-glucopyranosid)uronate

Guidance literature:: Multi-step reaction with 5 steps

1: 68 percent / AlCl₃, BH₃-Me₃N, 4 Angstroem molecular sieves / diethyl ether; CH₂Cl₂ / 1 h / 0 °C

2: pyridine, TFA, DCC / dimethylsulfoxide / Ambient temperature

3: PDC / dimethylformamide / Ambient temperature

4: 70 percent / MeONa / methanol / 24 h

5: 86 percent / pyridine / 20 h / 65 °C

With pyridine; dipyridinium dichromate; aluminium trichloride; trimethylamine-borane; 4 A molecular sieve; sodium methylate; dicyclohexyl-carbodiimide; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/jo00112a046