methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

Base Information

Chemical Name:methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate
CAS No.:1260144-22-6
Molecular Formula:C₂₂H₂₇FN₂O₅S
Molecular Weight:450.531
Hs Code.:

Synonyms:methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

Suppliers and Price of methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

There total 5 articles about methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1260144-21-5
methyl (S)-3-(4-hydroxybenzenesulfonylamino)-2-piperidin-1-ylpropanoate

: 459-46-1
4-Fluorobenzyl bromide

: 1260144-22-6
methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

Guidance literature:: With caesium carbonate; In acetone; at 20 ℃; for 18h;

Reference yield:

: 111712-04-0
4-phenylmethoxybenzenesulfonic acid sodium salt

: 1260144-22-6
methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

Guidance literature:: Multi-step reaction with 4 steps

1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 18 h / -20 - 20 °C

2: triethylamine / dichloromethane / 18 h / 20 °C

3: hydrogen; acetic acid / palladium 10% on activated carbon / ethyl acetate; 1,4-dioxane / 5 h / 20 °C / Inert atmosphere

4: caesium carbonate / acetone / 18 h / 20 °C

With oxalyl dichloride; hydrogen; caesium carbonate; acetic acid; triethylamine; palladium 10% on activated carbon; In 1,4-dioxane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetone;

Reference yield:

: 1260144-13-5
methyl(S)-3-(4-benzyloxybenzenesulfonylamino)-2-piperidin-1-ylpropanoate

: 1260144-22-6
methyl(S)-3-[4-(4-fluorobenzyloxy)benzenesulfonylamino]-2-piperidin-1-ylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen; acetic acid / palladium 10% on activated carbon / ethyl acetate; 1,4-dioxane / 5 h / 20 °C / Inert atmosphere

2: caesium carbonate / acetone / 18 h / 20 °C

With hydrogen; caesium carbonate; acetic acid; palladium 10% on activated carbon; In 1,4-dioxane; ethyl acetate; acetone;