Treloxinate

Base Information

Chemical Name:Treloxinate
CAS No.:30910-27-1
Molecular Formula:C₁₆H₁₂Cl₂O₄
Molecular Weight:339.175
Hs Code.:2918300090
NSC Number:162487
UNII:7YA71JCD50
DSSTox Substance ID:DTXSID90184909
Nikkaji Number:J20.517F
Wikidata:Q27269018
NCI Thesaurus Code:C72988
ChEMBL ID:CHEMBL2106496
Mol file:30910-27-1.mol

Synonyms:methyl 2,10-dichloro-1(2H)-dibenzo(d,g)(1,3)dioxocin-6-carboxylate;treloxinate

Suppliers and Price of Treloxinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL 2,10-DICHLORO-12H-DIBENZO[D,G][1,3]DIOXOCINE-6-CARBOXYLATE 95.00%
5MG
$ 500.76

Total 2 raw suppliers

Chemical Property of Treloxinate

Chemical Property:

Vapor Pressure:4.6E-10mmHg at 25°C
Boiling Point:498.3°Cat760mmHg
Flash Point:200.8°C
PSA：44.76000
Density:1.383g/cm³
LogP:3.85450
XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:338.0112642
Heavy Atom Count:22
Complexity:378

Purity/Quality:

95% ^*data from raw suppliers

METHYL 2,10-DICHLORO-12H-DIBENZO[D,G][1,3]DIOXOCINE-6-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1OC2=C(CC3=C(O1)C=CC(=C3)Cl)C=C(C=C2)Cl

Technology Process of Treloxinate

There total 4 articles about Treloxinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 67-56-1
methanol

: 30910-26-0
2,10-dichloro-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acid

: 30910-27-1
methyl 2,10-dichloro-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate

Guidance literature:: With sulfuric acid; Reflux;
DOI:10.1007/s00044-014-1021-1

Reference yield:

: 106-48-9,82344-39-6
4-chloro-phenol

: 30910-27-1
methyl 2,10-dichloro-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 3 h / 80 °C

2.1: potassium carbonate / isopropyl alcohol / Heating

2.2: 90 h / Reflux

3.1: sulfuric acid / Reflux

With sulfuric acid; potassium carbonate; In isopropyl alcohol;
DOI:10.1007/s00044-014-1021-1

Reference yield:

: 97-23-4
2,2'-methylenebis(4-chlorophenol)

: 30910-27-1
methyl 2,10-dichloro-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / isopropyl alcohol / Heating

1.2: 90 h / Reflux

2.1: sulfuric acid / Reflux

With sulfuric acid; potassium carbonate; In isopropyl alcohol;
DOI:10.1007/s00044-014-1021-1