2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

Base Information

Chemical Name:2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine
CAS No.:1314535-25-5
Molecular Formula:C₂₈H₂₀F₁₆N₆O
Molecular Weight:760.481
Hs Code.:

Synonyms:2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

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Chemical Property of 2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

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Technology Process of 2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

There total 3 articles about 2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1314535-07-3
2-isopropyl-7-phenyl-4-(prop-2-ynyloxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

: 62571-55-5
8-azido-1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorooctane

: 1314535-25-5
2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

Guidance literature:: With copper(l) iodide; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.ejmech.2011.05.011

Reference yield:

: 1314534-91-2
2-isopropyl-7-phenyl-5-(trifluoromethyl) pyrido[2,3-d]pyrimidin-4(3H)-one

: 1314535-25-5
2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; potassium iodide / acetone / 60 °C

2: copper(l) iodide / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere

With copper(l) iodide; potassium carbonate; potassium iodide; In tetrahydrofuran; acetone;
DOI:10.1016/j.ejmech.2011.05.011

Reference yield:

: 114085-00-6
2-amino-3-cyano-4-trifluoro-methyl-6-phenyl-pyridine

: 1314535-25-5
2-isopropyl-7-phenyl-4-((1-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-1H-1,2,3-triazol-4-yl)methoxy)-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / 120 - 130 °C

2: potassium carbonate; potassium iodide / acetone / 60 °C

3: copper(l) iodide / tetrahydrofuran / 24 h / 20 °C / Inert atmosphere

With copper(l) iodide; sulfuric acid; potassium carbonate; potassium iodide; In tetrahydrofuran; acetone;
DOI:10.1016/j.ejmech.2011.05.011