ethyl 5-bromo-2-fluorobenzoate

Base Information

• Chemical Name: ethyl 5-bromo-2-fluorobenzoate
• CAS No.: 612835-53-7
• Molecular Formula: C₉H₈BrFO₂
• Molecular Weight: 247.064
• Hs Code.: 2916399090
• Mol file: 612835-53-7.mol

Synonyms:ethyl 5-bromo-2-fluorobenzoate

Chemical Property of ethyl 5-bromo-2-fluorobenzoate

Chemical Property:

• Vapor Pressure: 0.00675mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

Ethyl5-Bromo-2-fluorobenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 5-bromo-2-fluorobenzoate

There total 3 articles about ethyl 5-bromo-2-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

→ ethyl 5-bromo-2-fluorobenzoate (612835-53-7)

Guidance literature:

Reference yield: 91.0%

ethanol (64-17-5) + 5-bromo-2-fluoro-benzoic acid (146328-85-0) → ethyl 5-bromo-2-fluorobenzoate (612835-53-7)

Guidance literature:

With sulfuric acid; In benzene; Cooling with ice; Reflux;

DOI:10.1002/cjoc.201190222

Reference yield: 84.0%

ethyl cyanoformate (623-49-4) + 1-Bromo-4-fluorobenzene (460-00-4) → ethyl 5-bromo-2-fluorobenzoate (612835-53-7)

Guidance literature:

1-Bromo-4-fluorobenzene; With 2,2,6,6-tetramethylpiperidinyl-lithium; magnesium chloride; In tetrahydrofuran; at 0 ℃; for 0.0111111h; Flow reactor; Inert atmosphere;

ethyl cyanoformate; In tetrahydrofuran; at 25 ℃; for 0.5h; regioselective reaction; Flow reactor; Inert atmosphere;

DOI:10.1002/anie.201502393

upstream raw materials:

ethanol

5-bromo-2-fluoro-benzoic acid

ethyl cyanoformate

1-Bromo-4-fluorobenzene

Downstream raw materials:

C₁₇H₁₈BrFO

1-deoxy-1-{3-[1-(4-ethoxyphenyl)-1-methylethyl]-4-fluorophenyl}-β-D-glucopyranose

2,3,4,6-tetra-O-acetyl-1-deoxy-1-{3-[1-(4-ethoxyphenyl)-1-methylethyl]-4-fluorophenyl}-β-D-glucopyranose

1-(5-bromo-2-fluorophenyl)-1-methylethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 612835-53-7 ethyl 5-bromo-2-fluorobenzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send