(RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide

Base Information

• Chemical Name: (RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide
• CAS No.: 942410-78-8
• Molecular Formula: C₁₀H₁₂N₂O₅S
• Molecular Weight: 272.282
• Mol file: 942410-78-8.mol

Synonyms:(RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide

Chemical Property of (RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide

There total 3 articles about (RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

imino(methyl)(3-nitrophenyl)-λ6-sulfanone (22133-02-4) + chloroformic acid ethyl ester (541-41-3) → (RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide (942410-78-8)

Guidance literature:

With pyridine; at 20 ℃; for 0.166667h;

Reference yield:

1-(methylsulfanyl)-3-nitrobenzene (2524-76-7) → (RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide (942410-78-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sulfuryl dichloride / dichloromethane / 4 h / -60 - -20 °C

2.1: sodium azide; sulfuric acid / dichloromethane / 24 h / 0 - 45 °C

2.2: 0 °C / pH 11

3.1: pyridine / 0.17 h / 20 °C

With pyridine; sodium azide; sulfuryl dichloride; sulfuric acid; In dichloromethane;

Reference yield:

methyl 3-nitrophenyl sulfoxide (132016-29-6,146143-21-7,3272-42-2) → (RS)-S-(3-nitrophenyl)-N-(ethoxycarbonyl)-S-methyl sulfoximide (942410-78-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium azide; sulfuric acid / dichloromethane / 24 h / 0 - 45 °C

1.2: 0 °C / pH 11

2.1: pyridine / 0.17 h / 20 °C

With pyridine; sodium azide; sulfuric acid; In dichloromethane;

upstream raw materials:

imino(methyl)(3-nitrophenyl)-λ⁶-sulfanone

chloroformic acid ethyl ester

1-(methylsulfanyl)-3-nitrobenzene

methyl 3-nitrophenyl sulfoxide

Downstream raw materials:

(RS)-N-(ethoxycarbonyl)-S-(3-{[5-bromo-pyrimindin-2-yl]amino}phenyl)-S-methylsulfoximide