1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol

Base Information

Chemical Name:1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol
CAS No.:1321562-49-5
Molecular Formula:C₁₄H₉Cl₃F₃NO
Molecular Weight:370.586
Hs Code.:

Synonyms:1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol

Suppliers and Price of 1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol

Chemical Property:

Purity/Quality:

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Technology Process of 1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol

There total 2 articles about 1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1321562-47-3
1-(4-amino-3,5-dichlorophenyl)-2,2,2-trifluoroethanone

: 873-77-8
(4-chlorphenyl)magnesium bromide

: 1321562-49-5
1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol

Guidance literature:: In tetrahydrofuran; at 0 ℃; Inert atmosphere;

Reference yield:

: 23516-79-2
4-(trifluoroacetyl)aniline

: 1321562-49-5
1-(4-amino-3,5-dichlorophenyl)-1-(4-chlorophenyl)-2,2,2-trifluoroethanol

Guidance literature:: Multi-step reaction with 2 steps

1: N-chloro-succinimide / acetonitrile / 1.5 h / Reflux

2: tetrahydrofuran / 0 °C / Inert atmosphere

With N-chloro-succinimide; In tetrahydrofuran; acetonitrile;