1321562-47-3Relevant articles and documents
Synthesis method of 3',5'-dichloro-2,2,2-trifluoroacetophenone derivative
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Paragraph 0028-0033, (2021/06/26)
The invention relates to the technical field of chemical pharmacy, in particular to a synthesis method of a 3',5'-dichloro-2,2,2-trifluoroacetophenone derivative, which specifically comprises the following steps: S1, preparing a Grignard reagent from a 1-bromo-3,5-dichloro-4-substituted compound through a Grignard reagent; and S2, subjecting a Grignard reagent and a trifluoroacetyl compound to a reaction, and then conducting acid treatment, so as to obtain the 3',5'-dichloro-2,2,2-trifluoroacetophenone derivative. According to the technical scheme, reaction conditions are mild, raw materials are easy to obtain, the yield is high, the production cost of enterprises can be saved, and the 3',5'-dichloro-2,2,2-trifluoroacetophenone derivative is suitable for large-scale production.
Preparation method of 3',5'-dichloro-2,2,2-trifluoroacetophenone
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Paragraph 0026-0028; 0030-0053; 0060; 0062, (2020/12/31)
The invention relates to the technical field of chemical pharmacy, particularly to a preparation method of 3',5'-dichloro-2,2,2-trifluoroacetophenone. According to the invention, 3',5'-dichloro-2,2,2-trifluoroacetophenone is prepared from 3'-chloro-2,2,2-trifluoroacetophenone as a raw material through four steps of nitrification, reduction, chlorination and deamination, and the method has the advantages of low raw material cost, mild reaction conditions, simple reaction process, facilitation of the reduction of the production cost, and improvement of the economic effect.
INSECTICIDAL COMPOUNDS
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Page/Page column 60, (2011/09/14)
The present invention relates to certain bisamide derivatives of formula (I), to processes and intermediates for preparing them, to insecticidal, acaricidal, nematicidal or molluscicidal compositions comprising them and to methods of using them to combat